Browsing by Type "other"
Now showing 1 - 20 of 339
Results Per Page
Sort Options
- Publication2023 MSG328 – Introduction to Modelling - July/August(2023-08)PPSM, Pusat Pengajian Sains MatematikSecond Semester Examination 2022/2023 Academic Session July/August 2023 MSG328 – Introduction to Modelling Duration : 2 hours [Masa : 2 jam] Please check that this examination paper consists of FIVE (5) pages of printed material before you begin the examination. Instructions: Answer all THREE (3) questions.
- Publication2023 MAT203 - Vector Calculus - July/August(2023-08)PPSM, Pusat Pengajian Sains MatematikSecond Semester Examination 2022/2023 Academic Session July/August 2023 MAT203 - Vector Calculus Duration : 2 hours Please check that this examination paper consists of THREE (3) pages of printed material before you begin the examination. Instruction: Answer all FOUR(4) questions.
- PublicationAirway epithelial barrier, mucins and inflammasome in distinct eosinophilic, neutrophilic and mixed inflammatory phenotypes of asthma(2018-01)Tze, Tan HernIntroduction Asthma is a complex, chronic respiratory disease with marked clinical and pathophysiological heterogeneity. Specific pathways are thought to be involved in the pathomechanisms of different inflammatory phenotypes of asthma, yet direct in vivo comparison has not been performed. In the present study, we aimed to investigate the expression of tight junction molecules, mucins and inflammasome activation in different phenotypes of airway inflammation. Method We developed models of three different phenotypes of airway inflammation in mice, namely · eosinophilic, mixed, and neutrophilic asthma via different methods of house dust mite , sensit isation and challenge. Transcriptome analysis was performed using whole lung tissues, fol lowed by quantitative RT-PCR, western blot analysis and confocal microscopy. Results By unbiased whole genome transcriptomic approach, we found that airway tight junction (TJ) molecules, mucins and inflammasome-related genes are differentially expressed in distinct phenotypes of allergic airway inflammation. Detailed analysis of several molecules from these families revealed that (i) Zo-1 and Cldn18 were downregulated in all phenotypes, while Cldn4 upregulation was characteristic for neutrophilic airway inflammation; (ii) mucins Clcal (GobS) and MucSac were upregulated in eosinophilic and even more in neutrophilic asthma, and (iii) upregulation of inflammasome-related molecules such as Nlrp3, Nlrc4, casp-1 and IL-113 was characteristic for neutrophilic asthma. Finally, we showed that inflammasome/Th· 17 /neutrophilic axis cytokines, namely IL-113 and IL-17, might impair epithelial barrier function and increase mucins expressions in primary hBECs from normal and asthmati< donors. Conclusion Our findings suggest that differential expression of TJs, mucins and inflammasome-relate<: molecules in distinct asthma phenotypes might be mechanistically linked and could further reflect the differences observed in the clinic.
- PublicationAptamer Technology: Adjunct Therapy for Malaria(2018-10)Kamarudin, Nik Abdul Aziz NikMalaria is a life-threatening parasitic infection occurring in the endemic areas, primarily in children under the age of five, pregnant women, and patients with human immunodeficiency virus and acquired immunodeficiency syndrome (HIV)/(AIDS) as well as non-immune individuals. The cytoadherence of infected erythrocytes (IEs) to the host endothelial surface receptor is a known factor that contributes to the increased prevalence of severe malaria cases due to the accumulation of IEs, mainly in the brain and other vital organs. Therefore, further study is needed to discover a new potential anti-adhesive drug to treat severe malaria thus reducing its mortality rate. In this review, we discuss how the aptamer technology could be applied in the development of a new adjunct therapy for current malaria treatment.
- PublicationCCS516 – Computational Intelligence (Kecerdasan Komputan)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCCS527 – Internet Of Things(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCCS528 – Information Security and Cryptography (Keselamatan Maklumat dan Kriptografi)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCDS501 – Principles & Practices of Data Science & Analytics (Prinsip & Amalan Sains Data & Analitik)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCDS502 – Big Data Storage and Management (Storan dan Pengurusan Data Raya)(2023-02)Pusat Pengajian Sains KomputerPusat Pengajian Sains Komputer (School Of Computer Sciences): Exam Papers/Teaching Resources
- PublicationCDS503 – Machine Learning (Pembelajaran Mesin)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCDS505 – Data Visualization & Visual Analytics (Data Visualisasi & Analitik Visual)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCDS511 - Consumer Behavioural and Social Media Analytics (Perilaku Pengguna dan Analitik Sosial Media)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCDS522 – Text and Speech Analytics (Analitik Teks dan Pertuturan)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCIT547 – Informatics Project Management (Pengurusan Projek Informatik)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCIT552 – Business Organisation and Environments (Organisasi dan Persekitaran Perniagaan)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCIT561 – Healthcare Information System (Sistem Maklumat Penjagaan Kesihatan)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCIT571 – Technopreneurship and Business Development (Pembangunan Tekno-keusahawanan dan Perniagaan)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCMT221 – Database Organisation & Design (Rekabentuk & Organisasi Pangkalan Data)(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session
- PublicationCMT221 – Database Organisation & Design (Rekabentuk & Organisasi Pangkalan Data) - February 2023(2023-02)Pusat Pengajian Sains KomputerFirst Semester Examination 2022/2023 Academic Session February 2023 CMT221 – Database Organisation & Design (Rekabentuk & Organisasi Pangkalan Data) Duration : 2 hours (Masa : 2 jam) Please check that this examination paper consists of SIX (6) pages of printed material before you begin the examination. [Sila pastikan bahawa kertas peperiksaan ini mengandungi ENAM (6) muka surat yang bercetak sebelum anda memulakan peperiksaan ini.] Instructions : Answer ALL questions. [Arahan : Jawab SEMUA soalan.] You may answer the questions either in English or in Bahasa Malaysia. [Anda dibenarkan menjawab soalan sama ada dalam bahasa Inggeris atau bahasa Malaysia.]
- PublicationCMT221 – Database Organisation & Design - February 2024(2024-02)Pusat Pengajian Sains KomputerPlease check that this examination paper consists of EIGHT (8) pages of printed material before you begin the examination. Instructions : Answer ALL FOUR (4) questions.