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  • Publication
    Sleep hygiene practice and sleep quality among undergraduate students in School of Health Sciences Universiti Sains Malaysia
    (2023-06)
    Solihudin, Nurul Izzah
    Undergraduate students are commonly vulnerable to suboptimal sleep quality due to increased academic demand. Sleep hygiene is a set of good sleep habits that is believed to be associated with sleep quality. A cross-sectional study was conducted to determine the level of practice of sleep hygiene, the level of sleep quality, and the association between sleep hygiene practice and sleep quality among undergraduate students in School of Health Sciences (SoHS), USM. The questionnaires used in this study were Sleep Hygiene Index (SHI) adopted from Mastin et al., (2006) and Pittsburgh Sleep Quality Index (PSQI) adopted from Buysse et al., (1989). A total of 201 undergraduate students who fulfilled the inclusion were involved in this study. They were selected by a simple random sampling method. Data collected were statistically analyzed by using the Statistical Package Social Science (SPSS) software version 26. This study shows that 116 (57%) respondents had poor sleep hygiene practice level. Meanwhile, 187 (93.0%) respondents have poor quality of sleep. This study also revealed that there is no significant association between sleep hygiene and quality of sleep among undergraduate students in School of Health Science, USM (p=0.243). This study’s finding demonstrated that most undergraduate students in School of Health Sciences USM have poor sleep hygiene and poor quality of sleep. Therefore, sleep education programs as an intervention and prevention strategy are suggested to improve sleep quality and adoption of sleep hygiene practice among students.
  • Publication
    System design optimisation of dual thrust solid rocket motor using pso algorithm
    (2023-04-01)
    Ahmed Mahjub M. Alhaj
    So far, chemical rocket propulsion is the only practical means to reach space. Among this rocket propulsion category, Solid Rocket Motor (SRM) placed itself well as the simplest and cheapest propulsion system compared to liquid and hybrid propulsion systems. The design of modern SRMs is a complicated and highly interactive process that involves significant trade-offs between competing objectives such as performance, cost, safety, size, weight, etc. One of these designs is the dual￾thrust single-chamber SRM (DT-SRM) that is used in several new rocket vehicles. In the literature, the design of DT-SRM has only been treated from the propellant grain perspective ignoring the inherent interaction with other motor design parameters.Moreover, most of these design models were numerical which increased the computational burden. Such approach is limited when implemented on a real-world problem, where all design parameters are affecting each other, and subsequently need to be optimized from a system point of view to give a more efficient and reliable design. Consequently, the ultimate goal of this thesis is to propose, validate, and implement a cost-effective and integrated system design optimisationframework to the preliminary design of DT-SRM based on the main motor design disciplines namely, casing, propellant grain, nozzle, and mass. To satisfy the condition of the dual thrust, an analytical mathematical model for the complex 3-D finocyl propellant grain shape is built and integrated to the other motor design models to form a system design model. The particle swarm optimisation (PSO) algorithm was utilized, with slight modification, in a multidisciplinary design optimisation (MDO) framework to search for the optimum design variables that minimize the total mass of the motor under specified performance and geometrical constraints. The validation results against existing test-firing data confirmed the reliability of the proposed system designoptimisation approach. The proposed approach was successfully implemented in thepreliminary design of a DT-SRM test case, where the performance simulation results of the optimized system showed an improved DT-SRM system design. As a complementary study, the design optimisation results were supported by a flight performance analysis using a six-degrees of freedom (6-DOF) simulation, in which the optimized DT-SRM was capable to deliver a certain payload to a certain distance in a stable flight path. The proposed approach represents an affordable and reliable tool to the preliminary design and optimisation of DT-SRMs intended to serve as a propulsion system for medium-size aerospace vehicles.
  • Publication
    Fractal analysis approach in the characterisation of cerebrovascular complexity in asymptomatic cerebral small vessel disease
    (2023-02)
    Aminuddin, Niferiti
    Cerebral small vessel disease (CSVD) refers to a spectrum of clinical and neuroimaging findings caused by pathological damage of small vessels of the cerebral parenchyma. Cerebral white matter hyperintensity (WMH) is one of the commonest neuroimaging findings of CSVD. Often, CSVD is diagnosed once the symptoms developed. Detection of the underlying vascular structural changes might facilitate early disease risk stratification and disease monitoring as vascular alteration precedes cerebral parenchymal injury. Of interest, fractal analysis allows us to quantitatively measure the complexity of the cerebral vascular structure in terms of fractal dimension (Df). The cerebral vascular Df changes are indicative of inefficient tissues perfusion which renders the cerebral parenchyma vulnerable to damage. The aim of this study is to explore a novel vascular neuroimaging marker of asymptomatic CSVD by characterising the complexity of the circle of Willis (CoW) and its tributaries as measured by Df. An exploratory cross-sectional study was conducted involving 22 subjects of age between 25 - 75 years old with low to moderate QRISK2 score who underwent magnetic resonance imaging/angiography (MRI/MRA) examination. These subjects presented with or without WMH. The cerebral vascular complexity of the MRA image was characterised using Df. The cerebral vascular Df was compared between asymptomatic subjects with (WMH+; n = 8) and without cerebral WMH (WMH-; n = 14). Furthermore, cerebral vascular Df was also compared between asymptomatic subjects with both CSVD risk factors and cerebral WMH (RF+ & WMH+; n = 6), subjects with CSVD risk factors only (RF+ & WMH-; n = 5), and subjects without both CSVD risk factors and cerebral WMH (RF- & WMH-; n = 9). Simple linear regression (SLR) was performed between QRISK2 score and cerebral vascular Df. Mean cerebral vascular Df was significantly lower in the WMH+ group than WMH- group. Moreover, the mean cerebral vascular Df of the RF+ & WMH- and RF+ & WMH+ groups were significantly lower than RF- & WMH- group. The SLR model had indicated that increased QRISK2 score significantly predicted reduction in cerebral vascular Df. The cerebral vascular Df was reduced in the subjects with CSVD risk factors and asymptomatic CSVD subjects with WMH. The SLR model had indicated that QRISK2 score significantly predicted cerebral vascular Df. The results indicate that cerebral vascular Df is a promising biomarker of asymptomatic CSVD subjects with WMH. Larger-scaled studies are required to explore its potential in a broader population setting.
  • Publication
    Development and validation of the measurement tools and health education module on knowledge and practices for dengue among kindergarten children in Kelantan
    (2023-03)
    Subramaniam, Neevaarthana
    Dengue had been classified as one of the longest existing vector-borne diseases in Malaysia. Community members of all age groups had been prone to dengue infection, however, awareness related studies on dengue among kindergarten children aged five to six years had not been widely explored. Hence, this study aims to assess knowledge and practice levels and test the educational intervention programmes for young children in urban, sub-urban and rural areas of Kelantan. To achieve the objective, this study consisted of a cross-sectional and interventional study design which was conducted in four different phases. In Phase I, a guided interview-based questionnaire with 40 initial items to measure knowledge and practice levels was developed. Flashcards representing the illustration for selected items were also developed. The interview-based questionnaire was then validated and revised through content validity and face validity. The revised interview-based questionnaire was proceeded for item, factor and reliability analysis. The finalised interview-based questionnaire was then pre-tested following a cross-sectional study design among randomly selected 200 kindergarten children. In Phase II, a total of 396 kindergarten children were recruited to obtain knowledge and practice levels using the pre-validated interview-based questionnaire. Next, in Phase III, activity-based and module-based intervention programmes were developed, validated by experts and revised accordingly. In Phase IV, the revised activity and module intervention programmes were proceeded to be tested among 46 and 72 kindergarten children, respectively. Data from all the phases were analysed using the Statistical Package of the Social Sciences (SPSS) according to the respective tests needed to produce the results. For the outcome of this study, the final version of questionnaire consisted of 33 items, with a good internal consistency of Cronbach Alpha of 0.788. Through the measurement of knowledge and practice, practice levels were seen to be significantly higher in both urban and sub-urban areas compared to the rural area (p < 0.05). Significant differences (p < 0.001) were observed in both knowledge and practice scores among participants after implementation of educational intervention programmes. Therefore, this study concludes that the approach using the interview-based questionnaire and the specifically designed educational intervention programmes are effective. They can be considered valid and reliable study instruments for early exposure of dengue knowledge and practices among kindergarten children aged five to six years old.
  • Publication
    Removal of arsenic from aqueous solution by various natural soil-based adsorbents
    (2023-03)
    Fairuz, Farah Shahirah Mohd
    Rapid industrialization, mining and agricultural activities lead to the release of contaminants such as arsenic (As) into the water sources that causes adverse effect to living organism. Thus, the application of effective and efficient removal method is crucial. The objective of the study is to apply the adsorption method by utilizing natural soil-based adsorbents including red, clay, sandy and black soil for removal of arsenic from aqueous solution. This study involved the characterisation of heavy metal content and physicochemical characteristic of soil adsorbents, followed by batch adsorption process and the study of adsorption model and mechanism. The results for concentration of arsenic in all soil adsorbents were lower than the permissible limit stated by European United (EU) and mean concentration of iron (Fe) observed to be higher in red soil compared to in other soil samples. For the physicochemical characterisation analysis, red soil has highest number of functional group, content of Fe based minerals, surface area and pore volume with the smallest particle size. From this study, the optimum removal conditions of arsenic from aqueous solution were 2.2 g/50 mL dosage of adsorbents for 60 minutes of contact time at pH of 5.5±0.5 and temperature of 40°C. The adsorption capability and efficiency of soil adsorbent in removing arsenic from aqueous solution were red soil> clay soil> sandy soil> black soil. The kinetic, isotherm and thermodynamic model showed that the mechanism of adsorption of arsenic was a chemisorption, non-spontaneous and endothermic process.
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  • Publication
    The relationship between physical activity and emotional status of pre-school children during school hour
    (2016-06)
    Yaacob, Khairun Shahira Mat
    Physical activity brings a lot of health benefits for all including children. Several chronic diseases such as diabetes mellitus, obesity, coronary heart disease (CHD) and hypertension can be avoided by doing regular exercise along with healthy diet. Physically active lifestyle during childhood and adolescence may contribute to the lower risk of having health problems during adulthood. 60 minutes of moderate to vigorous intensity physical activity daily recommended by World Health Organization (WHO) will improve children's cardiorespiratory and muscular fitness. Physical activity is essential for pre-school children for obesity prevention and to increase gross motor, fine motor, cognitive and social­emotional skills. This study aimed to determine the relationship between physical activity level and emotional status of pre-school children during school hour. Thus, pre-school students (n=33), (18 boys and 15 girls) aged 4 to 6 years old were recruited in this study. Parameter measured to determine physical activity level was steps count (weekdays only) using accelerometer GTX3+. As for the emotional status measurement, scores from the questionnaires; "Borang Soal Selidik Tingkah Laku Kanak-kanak" was used. Based on the result, the total step counts per week spent by the pre-school children were 10784 ± 3487. Sedentary activity was found as the most activity (723 ± 161) the children spent during school hour compared to the moderate activity (375 ± 119), light activity (266 ± 59), vigorous activity (4 ± 6) and very vigorous activity. Result found a significant difference of total steps count per week between boys and girls with p< 0.05. As for the types of activity, there was no significant difference of sedentary activity (p=0.646), light activity (p=0.126), vigorous activity (p=0.054) and very vigorous activity (p=0.533) between boys and girls. Scores from the questionnaires showed that all the children involved in this study has good emotional status with the score of ( 44.30 ±2.82). However, as comparison between genders was made, it showed that girls have better emotional status compared to boys. When mean of an emotional status between ages was compared, four years old children had the most stable emotional status followed by the six and five years old children. As for the relationship between physical activity and emotional status, we found that there was no significant correlation between them (p= 0.200, r= -0.229).
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    A pilot study of mental health intervention programme in primary health carein two districts of Kelantan
    (Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia, 1993)
    Zain, Azhar Md
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    Determination of lymphocyte subjects in patients with major depressive disorder (MDD)
    (Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia, 2018-01)
    Sanusi, Siti Nor Fairus Mohamed
    Major depressive disorder (MDD) has been associated with dysregulation of immune system. While many studies on activation of innate immune response currently dominates the research area, the dysregulation in adaptive immune system especially in circulating lymphocyte subsets has rarely been explored. Some studies indicated that the severity of MDD is important with respect to the extent of the immune changes in MDD patients. The objective of this study was to determine the predisposing factors of MDD and the common symptoms in MDD patients based on Beck Depression Inventory (BDI) and Montgomery-Asberg Depression Rating Scale (MADRS), and to determine the percentage and absolute count of lymphocyte subsets in MDD patients and their comparison between different severity of the disease. This study involved 47 MDD patients recruited from Psychiatric Clinic, Hospital Universiti Sains Malaysia (HUSM) and 47 healthy controls. MDD patients were diagnosed according to Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-V) criteria. The symptoms and severity of MDD was assessed using BDI and MADRS scale. The percentage and absolute count of CD4+ T cells, CD8+ T cell, CD4+ CD25+ Tregs, CD4+ CD25+ Foxp3+ Tregs, CD16+ CD56+ NK cells and CD19+ B cells were determined by using immunophenotyping technique. Mann-Whitney test was used to compare the percentage and absolute count of lymphocyte subsets between MDD patients and healthy controls. Kruskal-Wallis test was used to compare the percentage and absolute count of lymphocyte subsets between different severity of MDD. The results showed that those married, smoker, possess lower educational level and living in rural area have higher risk for MDD. Based on BDI, the most common symptoms reported by our MDD patients were fatigue and irritability. While based on MADRS, MDD patients also have inner tension, concentration difficulties, inability to feel and pessimistic thought. This study showed that there were no significant differences in the percentage and absolute count of CD4+ T cells (p=0.148; p=0.190), CD8+ T cells (p=0.316; p=0.783), CD16+ CD56+ NK cells (p=0.731; p=0.530), and CD19+ B cells (p=0.136; p=0.148) between MDD patients and healthy controls. However, we found a significatly higher percentage and absolute count of CD4+ CD25+ Tregs (p<0.001) and CD4+ CD25+ Foxp3+ Treg cells (p=0.003; p=0.001) in MDD patients compared with healthy controls. This study also showed that there were no significant differences in the percentage and absolute count of lymphocyte subsets between mild, moderate and severe MDD patients.
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    Peperiksaan Perkhidmatan Pembantu Keselamatan Kp19 Kertas II (Teori) - 2019
    (2019-10-31)
    Tarikh : 31 Oktober 2019 (Khamis) Masa : 2.30 petang – 4.30 petang (2 jam) Tempat : Kampus Induk & Kampus Kejuruteraan
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    Peranan Industri Kecil Dalam Pembangunan Desa Di Wilayah KEDA: Satu Penilaian Tidak Komprehensif
    (Universiti Sains Malaysia, 1984)
    Tujuan kajian ini ialah untuk menilai sejauhmana matlamat yang KEDA rancangkan telah tercapai . Adakah dengan terdirinya industri kecil ini pendapatan penduduk telah meningkat ; mutu kehidupnn telah berubah ; dan seterusnya peluang-peluang pekerjaan dapat diwujudkan yang dapat menyekat penghijrahan belia-belia ke bandar . Kajian ini juga bertujuan untuk membuat perbandingan diantara mereka menjadi semakin luas lagi . Hasil daripada rancangan pembangunan yang diadakan tidak membuahkan kejayaan yang yang terlibat secara langsung iaitu pekerja kilang dan mereka yang terlibat secara tidak langsung yang terdiri dari mereka yang mengambil upah nenganyam dan juga penebang buluh. Hasil kajian menunjukkan bahawa dengan terdirinya industri buluh ini, ia telah dapat membawa perubahan-perubahan atau kesan positif kepada mereka yang terlibat samada secara langsung atau tidak langaung.