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Exploring Caspase-Independent Apoptosis Mechanism Of New -Carboline Derivatives In Chronic Myelogenous Leukemia

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dc.contributor.authorNageswararao, Meroshine
dc.date.accessioned2026-07-21T08:10:47Z
dc.date.available2026-07-21T08:10:47Z
dc.date.issued2025-09
dc.description.abstractCancer is known as one of the serious causes of mortality among the world population. One of the most reliable treatments for cancer is chemotherapy, though drug resistance and severe side effects have caused major setbacks to effective treatment. Lately, it has been found that understanding the mechanism of action of a chemotherapy agent might lead to a more effective treatment for this disease which is named as targeted therapy. In the constant search for new anticancer agent alternatives, β-carboline alkaloids have been identified as good candidates for a new chemotherapy drug. β-carboline compounds M25, M56 and M62 were synthesised, and their purities were confirmed using gas chromatography-mass spectrometry (GC-MS) analysis
dc.identifier.urihttps://erepo.usm.my/handle/123456789/24749
dc.language.isoen
dc.subjectExploring Caspase-Independent Apoptosis Mechanism Of New -Carboline Derivatives
dc.subjectChronic Myelogenous Leukemia
dc.titleExploring Caspase-Independent Apoptosis Mechanism Of New -Carboline Derivatives In Chronic Myelogenous Leukemia
dc.typeResource Types::text::thesis::master thesis
dspace.entity.typePublication
oairecerif.author.affiliationUniversiti Sains Malaysia
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