Publication: Study of calcium salt coating on mechanical and bioactivity properties of bg45s5/cordierite
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Date
2024-08-01
Authors
Khoo Xhu Hearn
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Abstract
The BG/cordierite composite has an improved mechanical properties over pure BG45S5, though its bioactivity which is a critical feature for medical applications is reduced. This study explores the fabrication and evaluation of a Bioactive Glass 45S5 (BG45S5) and cordierite composite coated with hydroxyapatite (HA) for potential use in bone tissue engineering. The fabrication process involved forming BG45S5 and cordierite powders, combining them into a pellet, and treating them with varying concentrations of calcium salt solutions before immersion in simulated body fluid (SBF). X-ray Diffraction (XRD) indicated the initial amorphous state of BG45S5, which crystallized upon sintering, while cordierite remained crystalline. Bioactivity was confirmed by the presence of carbonate apatite peaks in calcium-treated samples post-SBF immersion. Fourier Transform Infrared Spectroscopy (FTIR) identified functional groups that supported bioactivity. The composite's mass loss in SBF suggested dissolution behavior and apatite formation, with higher calcium salt concentrations enhancing bioactivity. Density and porosity measurements indicated that more calcium salt led to more porous structures, aiding bone integration. An initial rapid pH increase in SBF due to calcium ions, which stabilized over time, reflected the composite's interaction with the fluid. Diametral Tensile Strength (DTS) tests showed that calcium salt treatment improved mechanical properties, with higher concentrations yielding greater tensile strengths. The BG45S5/cordierite composite demonstrates potential for bone tissue engineering, combining enhanced bioactivity and mechanical integrity.