Preparation And Characterization Of Citric Acid Cross-Linked Carboxymethylcellulose Hydrogel
Loading...
Date
2021-07-01
Authors
Tan Kai Qi
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Hydrogel is a network of water-containing flexible polymer chains physically
or chemically cross-linked in three-dimensional form. Citric acid cross-linked
carboxymethyl cellulose (CMC) hydrogels have attracted attention for their
biodegradability, high mechanical stability, and good water-absorbing ability. In this
study, citric acid cross-linked CMC hydrogel was prepared using different preparation
methods to enhance its physical and mechanical properties. The citric acid cross-linked
CMC hydrogel was prepared by varying the concentration of CMC at 2, 3, and 4 w/v % and varying the concentration of citric acid at 10, 15, and 20 mol/mol %. The stirring
condition of hydrogel was varied at room temperature and heating (50 - 55 °C); while
the drying condition of hydrogel was varied at fridge-dried (4 °C) and oven-dried (60 °C). The SEM and BET analysis revealed that the hydrogel is non-porous and water
absorption occurred via hydrogen bonding between water and CMC molecules. It is
proven that a higher concentration of CMC and citric acid increased the cross-linking
density. High cross-linking density significantly decreased the swelling ratio and
degradation ratio. The hydrogel composition of 4 w/v % CMC 20 m/m % citric acid
prepared by stirring at a heating condition and oven-dried was the most stable hydrogel
with a swelling ratio of 1879.89 % and a low degradation ratio of 12.07 %.