The influence of different dopants substitution into carbonated htdroxyapatite (CHA) structure
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Date
2019-07
Authors
Nur Nabilah Afja bt Mohd Afandi
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Abstract
Mg-doped CHA and Sr-doped CHA were synthesized via nanoemulsion method as this method was simple and can be carried out at room temperature. In this study, different amount of carbonate was used to synthesise CHA in order to get the optimize amount carbonate. The aim of introducing magnesium and strontium into carbonated hydroxyapatite structure was to study the effect size of dopants that been introduced into apatite structure. CHA was used as a control set for Mg-doped CHA and Sr-doped CHA. CHA x = 2.4 was chosen as the optimized amount of carbonate to synthesise doped CHA. There were three different compositions of dopants were used which were 0.1, 0.2 and 0.3 in order to synthesise Mg-doped CHA and Sr-doped CHA. All the doped CHA that been synthesized remained as B-type CHA with nanosize powders. All the as-synthesized powders were characterized in terms of elementally, physically and biologically. For bioactivity test, all the powders been palletized before soaked in the Simulated Body Fluid (SBF) solution for 7 days. After soaking, all the sample have successfully formed apatite layer on the surface of pellet after observed under FESEM. Thus, Sr CHA 0.1 showed good bioactivity properties as the formation of apatite was faster compared to other samples.