Fabrication And Characterization Of Agar Based Anthropomorphic Ultrasound Breast Phantom

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Date
2012-03
Authors
Foroozandehasl, Seyedeh Parisa
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Publisher
Universiti Sains Malaysia
Abstract
An anthropomorphic agar based breast phantom including tissue mimicking (TM) non adipose glandular tissue, TM fat and TM cyst was been fabricated. The fabricated phantom was characterized and the weight composition, temperature, frequency and time dependencies of the phantom were investigated. The sound speed and attenuation coefficient were measured by using the transmission substitution technique with three broadband transducers with 2.25, 5 and 10 MHz frequencies. Acoustic impedance, reflection coefficient and bulk modulus of fabricated breast phantom were also assessed. The sound speed, in fabricated agar based breast phantom, as a function of increasing weight composition of agar was increased across the range from 1487 ms-1 to 1540 ms-1. Attenuation coefficient was increased from 0.66 to 0.90 dB cm-1 MHz-1 for 2.25 MHz, 0.66 to 1.71 dB cm-1 MHz-1 for 5 MHz and 1.10 to 2.46 dB cm-1 MHz-1 for 10 MHz. Acoustic impedance, reflection coefficient and bulk modulus also increased with increasing concentration of agar. The sound speed of fabricated breast phantom increased by increasing the weight composition of alcohol, across the range from 1483 to 1510 ms-1. Attenuation coefficient increased from 0.10 to 0.23 dB cm-1 MHz-1 for 2.25 MHz, 0.34 to 0.59 dB cm-1 MHz-1 for 5 MHz and 0.85 to 0.92 dB cm-1 MHz-1 for 10 MHz. Acoustic impedance, reflection coefficient and bulk modulus also increased with the increasing percentage of alcohol. Increasing the weight composition of anise oil caused the reduction in the sound speed in the range of 1517 ms-1 to 1501 ms-1. Attenuation coefficient increased from 0.15 to 1.02 dB cm-1 MHz-1 for 2.25 MHz, 0.47 to 1.89 dB cm-1 MHz-1 for 5 MHz and 0.87 to 2.76 dB cm-1 MHz-1 for 10 MHz. Acoustic impedance, reflection coefficient and bulk modulus decreased with the increasing percentage of anise oil. The sound speed showed an increment trend with temperature across the range of 1466 to 1602 ms-1. Attenuation coefficient was found to decrease by increasing the temperature by a rate of 0.003 dB cm-1 MHz-1 °C-1. Acoustic impedance, reflection coefficient and bulk modulus increased with temperature. As a function of frequency, sound speed, acoustic impedance, reflection coefficient and bulk modulus all remained almost constant with increasing frequency but the attenuation coefficient increased significantly by increasing frequency.
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Keywords
An anthropomorphic agar based breast phantom , tissue mimicking non adipose glandular tissue
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