Development of nomogram for Malaysian pregnant women

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Date
2009-12
Authors
Ramli, Ramzun Maizan Binti
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Abstract
In this retrospective study, nomograms were developed for Malaysian pregnant women of singleton pregnancy with minor studies done for twin gestations. A number of 11052 Malaysian pregnant women were involved with 10935 women were singleton and 117 women were multiple pregnancies. The data collection was done at the Maternity Unit, Hospital Pulau Pinang. Analyses of data were performed using SPSS software version 11.5. The ANC (except Hb) and ultrasound (except AFI) parameters were grossly increased throughout the pregnancies. Highly R! values were noticed for generated models. Greater growth rate of BPD, HC, AC and FL for second trimester were noticed compared to third trimester but opposite result was found for EFW. Decrease of AFI values is seen after 28 weeks of GA towards the end of pregnancy. More factors were seen affecting the ANC values (ethnic, working status, gravida, delivery method, Apgar score, BL, PW, BW, LB and HCB) but less for ultrasound parameters (affected only to PW, BW, LB and HCB). The blood groups of the women show no effect for all parameters in ANC and ultrasound. Diseases such as diabetes mellitus and heart disease were noticed to have significant impact on ANC and ultrasound parameters during pregnancy. Comparisons of ultrasound parameters in this study with various studies show more significant difference results (106 studies; 68.83%) except for CRL. This suggests that every population should use their own ultrasound biometry assessment except in the first trimester. In this study, as for twin cases, higher ANC (except Hb), BL, PW; pulse and BP after delivery values were shown but with lower ultrasound parameters, BW, LB, HCB and TSH were noticed compared to singleton pregnancies. Most of the parameters studied also show significant differences between twin and singleton pregnancies. Findings from this study will help the medical practitioner in this country to predict the outcome of pregnancy earlier thus improving the foetus and mother health during pregnancy.
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Nomogram , Malaysian pregnant women
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