Effect of aging condition on the synthesis of 54s4p bioactive glass through sol-gel rout

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Date
2019-05
Authors
Deborah Odette Moizin
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The golden standard 45S5 BG has been intensively studied by many researchers. However, a recent novel composition of bioactive glass which is 54S4P (54 wt.% SiO2, 22 wt.% CaCO3, 20 wt.% Na2O, 4 wt.% P2O5) was successfully fabricated through melt-derive method. Melt-derived 54S4P BG had lower melting temperature compared to 45S5 BG and its properties had shown to be comparable with 45S5 BG. 54S4P BG was fabricated through sol-gel method and the effect of aging on the structural, bioactivity, and morphology of 54S4P BG was studied by varying the aging condition. The aging time was varied for 3 days, 7 days, 10 days and 14 days at room temperature. Whereas, the aging temperature was varied for 3 days at room temperature, 40 ˚C and 60 ˚C. The DSC-TGA result confirmed the stabilization temperature of 54S4P bioactive glass at 700 ˚C. XRD showed combeite high (Ca4Na4O18Si6) was the major crystalline phase. Results obtained from XRD and FTIR before the immersion in HBSS showed sharper and more definite peaks at decreasing aging time due to lower water content. But increasing aging temperature showed stronger and more intense peaks due to the formation of larger and coarser particles. SEM only showed the existence of needle-like crystals belonging to Ca4Na4O18Si6 in samples aged at lower temperature, room temperature. The existence of HA can be confirmed though FTIR, FESEM-EDX and pH evolution after immersion of 54S4P BG in HBSS. Hence, 54S4P has great potential to be used in the medical field.
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