Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease

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dc.contributor.authorLim, Hui Ting
dc.date.accessioned2021-07-28T04:18:53Z
dc.date.available2021-07-28T04:18:53Z
dc.date.issued2020-06
dc.description.abstractUsing an inducible Drosophila AD model by human Aβ42 expression with UAS/GAL4 system, the study was carried out to evaluate the effects of probiotic administration on the survival and mobility of female Drosophila melanogaster with AD. Evaluated by survival assay, the administration of L. fermentum DR9 for 24 days improved survival by increasing the survival percentage of female D. melanogaster AD model, as compared to the untreated control. Evaluated by the negative-geotaxis climbing assay, the administration of L. fermentum DR9 for 20 days improved the mobility of female D. melanogaster AD model in terms of climbing ability and climbing speed, by declining at a slower and more constant rate as compared to the untreated control.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/13854
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectEffects Of A Lactobacilli Probioticen_US
dc.subjectSurvival And Mobilityen_US
dc.subjectFemale Drosophila Melanogasteren_US
dc.subjectAlzheimer’s Diseaseen_US
dc.titleEffects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Diseaseen_US
dc.typeOtheren_US
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