Pusat Pengajian Sains Perubatan - Tesis

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Browsing Pusat Pengajian Sains Perubatan - Tesis by Subject "ACR TI-RADS"

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    Association between sonographic characteristics of cervical lymph nodes, suspicious thyroid nodules on acr ti-rads and its cytology findings
    (2021)
    Samin, Hidayatti S
    Background: Thyroid nodule is one of the most widespread endocrine disorders, and approximately 5% are malignant. The most common type of thyroid cancer is differentiated thyroid cancer which often metastasises to the cervical lymph node. Characterisation of thyroid nodules using ACR TI-RADS with a comprehensive ultrasound of cervical lymph nodes could help accurately predict malignancy of the suspicious thyroid nodules. The purpose of this study is to evaluate the association between sonographic characteristics of cervical lymph nodes and suspicious thyroid nodules on ACR TI-RADS in predicting thyroid malignancy and their correlation with cytology findings. Methods: A prospective study was conducted in Hospital Universiti Sains Malaysia (USM), Kota Bharu, Kelantan, Malaysia, on 52 patients who had suspicious thyroid nodules and were scheduled for FNAC procedure. The thyroid nodule was reassessed and characterised using ACR TI-RADS, classified into TR3, TR4, and TR5. The characteristic of cervical lymph nodes was determined using ATA and 2013 ETA guidelines, divided into normal, intermediate, and suspicious nodes. The cervical lymph node characteristic was then compared with the cytology findings of suspicious thyroid nodules. The association between suspicious thyroid nodules on ACR TI-RADS and characteristics of cervical lymph nodes had been carried out using Fisher’s Exact test analysis. Results: There is no significant association between suspicious thyroid nodule on ACR TI-RADS and characteristic of cervical lymph node, suspicious thyroid nodule on ACR TI-RADS, and suspicious cervical lymph node in correlation with cytology finding of thyroid nodule with the p-value of (p=0.494), (p=0.452) and (p=1.000) respectively. Conclusion: Our study shows no significant association between sonographic characteristics of cervical lymph nodes and suspicious thyroid nodules on ACR TI-RADS, association between suspicious thyroid nodules on ACR TI-RADS and cytology findings as well as association between suspicious cervical lymph nodes and cytology of the suspicious thyroid nodule. However, further research with a more substantial number of sample sizes could demonstrate the suspicious thyroid nodule on ACR TI-RADS and the characteristic of cervical lymph node association in predicting thyroid malignancy.