Pusat Pengajian Sains Kimia - Tesis
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- PublicationStudy Of Calcium Alginate-Silica Composite Beads In Transesterification Of Bleached Oil: Catalyst Modification, Optimization And Conversion To Renewable Hydrocarbon(2025-08)Ab Halim, Ainnur RusydinaSpent bleaching earth (SBE), a solid waste generated by vegetable oil refining industries, poses significant environmental and disposal challenges due to its high oil content. This study explores the valorization of SBE as both a catalyst support and a feedstock for biodiesel production, offering a sustainable waste management solution. A novel alginate–SBE composite catalyst was synthesized via a simple impregnation method under optimal conditions, using a 1:4 ratio of sodium alginate to SBE/KOH (25%, 30% & 35%), followed by calcination at 600 °C.
- PublicationDesign, Synthesis, In Silico And In Vitro Evaluations Of New Inhibitors Targeting Human Hypoxia Inducible Factor (Hif) Prolyl Hydroxylase Domain (Phd) Enzymes(2025-09)Mohammad, Sayaf AbrarHypoxia inducible factor (HIF) prolyl hydroxylase domain (PHD) enzymes play a pivotal role in oxygen sensing and regulation, making them key therapeutic targets for hypoxia-related diseases, including cardiovascular diseases (CVDs), chronic kidney disease (CKD), and anemia. However, current PHD inhibitors suffer from significant limitations, including toxicity, thromboembolic risks, and poor selectivity, necessitating the discovery of safer and more effective alternatives. This research utilises a computational-experimental methodology to discover new PHD inhibitors through the integration of molecular docking, molecular dynamics (MD) simulations, and free energy calculations, QSAR modeling, and experimental validation.
- PublicationFerrite-Based Oxides: Preparation, Characterization And Carbon Dioxide Adsorption Study(2025-09)Sulaiman, Nur IzzanaIn response to the growing demand for effective carbon capture technologies, this study investigates the synthesis and characterization of ferrite–based oxides solid adsorbents prepared using a facile sol-gel method. The primary aim is to enhance the adsorption capacity, reusability and structural properties of the adsorbent. Besides, ternary and quaternary ferrite–based oxides have seen limited exploration in the field of carbon capture, largely due to the prevalence of studies focusing on simpler single metal oxides. These complex multi-metal systems offer the potential for enhanced CO2 adsorption properties yet remain underutilized. In this study, inverse spinel ferrite along with M-type and W-type hexaferrite adsorbents, were successfully synthesized using low-cost, facile and efficient method.
- PublicationDevelopment Of Polyvinyl Alcohol/ Microcrystalline Cellulose/ Anthocyanin Biofilm As Ph-Sensitive Indicator For Smart Packaging(2025-09)Mohd Nor Azam, Nur AdrianaRecent studies have highlighted the negative environmental effects of petroleum-based plastics, emphasizing the increasing demand for biodegradable and smart food packaging materials. A sustainable and pH-sensitive food packaging film based on polyvinyl alcohol (PVA, 8%), microcrystalline cellulose (MCC, 2%), and anthocyanin (9% w/w) was developed using a solvent casting method in this study.
- PublicationBismuth Oxybromide-Based Composites Integrated Biochar From Palm Oil Mill Effluent Sludge For Photocatalytic Remediation Of Ciprofloxacin In Aqueous Medium(2025-09)Abdul-Raheem, Maryam NikeBismuth oxybromide (BiOBr) is a promising semiconductor with a narrow band gap (~2.7–2.9 eV), making it an attractive photocatalyst for various applications. However, its practical use is limited by low surface area, high electron-hole recombination rate, restricted visible light absorption, and difficulty in reuse. This study addresses these issues by developing BiOBr-based composite systems with enhanced photocatalytic performance for the treatment of pharmaceutical wastewater, using ciprofloxacin (CIP) as a model contaminant. A sustainable BiOBr-biochar composite (BBC) was synthesized via a solvent-free hydrothermal method using biochar derived from palm oil mill effluent sludge (POMES) as a support matrix.