Pusat Pengajian Sains Farmasi - Geran Penyelidikan
Browse
Recent Submissions
Now showing 1 - 5 of 7
- ItemCost-effectiveness of warfarin medication Therapy adherence clinic (WMTAC) versus usual Medical clinic (UMC) at Kuala Lumpur Hospital.(2014)Shafie, Asrul AkmalSystematic anticoagulation management clinic is now recommended to manage warfarinized atrial fibrillation (AF) patients. In Malaysia, the service is recently introduced as pharmacist managed Warfarin Medication Therapy Adherence Clinic (WMT A C). The objective of the present study was to assess the cost effectiveness of anticoagulation clinic in comparison with usual medical in Kuala Lumpur Hospital (KLH). KLH is 2302 bedded government tertiary referral hospital in Malaysia.
- ItemAssessement on the prophylactic and therapeutic potential of the antisense oligodeoxynucleotide To Icam-L In Acute renal failure.(2003)Zubaid, MunavvarIschaemia-reperfusion injury refers to injury that occurs in cells or tissues when the particular tissue region/organ is subjected to a prolonged period of oxygen deprivation (ischaemia), followed by immediate reoxygenation (reperfusion). It has been well documented that prolonged ischaemia is capable of causing cell swelling, vasoconstriction and rapid tissue necrosis (Thadani et.al., 1996).
- ItemStudy of molecular pathways mediating the anti-cancer efficacy of koetjapic acid isolated from sandoricum koetiape against human colon cancer xenograft in immunocompromised mice.(2014)Abdul Majid, Amin Malik ShahTaking the promising chemotherapeutic efficacy of potassium koetjapate, the results of the present study suggests and recommends to proceed further research activities on potassium koetjapate using clinical trails phase I~ II and ill to evaluate the safety, effective dose and therapeutic efficacy in human patients.
- ItemElectrophiles and Michael acceptors as Nrf2 modulators in a Caenorhabditis elegans model.(2016)Chong Yew, LeeAmyloid-beta (AI3) toxicity has been proposed and demonstrated to be a key contributor to the neurodegenerative process in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD).The mechanisms by which AI3 leads to neuronal damage and dysfunction are still not well understood. Ketoksikan Amiloid beta (A!3) didapati satu penyumbang kepada proses neurodegenerasi dalam pathogenesis penyakit Alzheimer. Mekanisme bagaimana A!3 membawa kepada kerosakan neuron masih kurang difahami.
- ItemSynthesis and Biological Evaluation of Aurones as Potential Neuroprotective Agents: Structure-activity and Mode of Action Studies.(2016)Chong Yew, LeeA series of aurone derivatives carrying amine and carbamate functionalities at various positions of the scaffold was designed and synthesized with the premise of developing a reasonably small sized multitargeting compound for neuroprotection while maintaining good drug-like properties.