Pusat Pengajian Sains Kesihatan - Dataset

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    Evaluation of serai kayu (Sygyzium polyanthum) leaves extract as blood pressure lowering agent in hypertensive rat’s model.
    (2017)
    Jamal, Norfazirah
    Syzygiumpolyanthum or “serai kayu” is popular among Kelantanese as traditional antihypertensive medicine. This study aimed to evaluate the effects of oral crude aqueous and methanol extracts of S.polyanthum (AESP and MESP, respectively) on blood pressure of spontaneous hypertensive rat (SHR) and the histopathology improvements on the kidney of treated-SHR. AESP and MESP were prepared using ultrasound-assisted (sonication) extraction technique. The changes of systolic blood pressure (SBP) were recorded using non-invasive technique (tailed cuff method) over period of 24 h (acute study) and 6 week (subacute study) of daily gavage. The kidney histopathology was evaluated at the end of subacute study using hematoxylin and eosin (H&E) stain. AESP at 1750 mg/kg significantly reduced SBP in the acute study (p<0.001). Similarly, MESP at 2000 mg/kg significantly reduced SBP (p<0.001). For subacute study, both AESP and MESP (at 1750 mg/kg and 2000 mg/kg, respectively) significantly reduced SBP started at week 2 (p<0.001) and continue up until week 6 of intervention (p<0.00l). In histopathology assessment, the kidney of MESP-treated SHR showed a well-preserved glomerulus and well capsulated Bowman’s capsule. In contrast, AESP did not showed the similar improvements. These results showed that despite both extracts had similar profile on blood pressure reduction, only MESP improved the histopathology of the kidney and to be potential antihypertensive agents.
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    Publication
    Selected health related fitness in female underfraduate students.
    (2009-04)
    Mohamed, Nazirah Gulam
    To describe and compare the health-related physical fitness of young females based on body mass index (BMI) classifications. Anthropometric indices, including height, weight, waist and hip circumferences were assessed in a cross-sectional study of35 healthy female undergraduate students aged 20-22 years. Blood pressure was measured using a sphygmomanometer, while cardiorespiratory fitness (CRF) was estimated using the 20m multi-stage fitness test. The BMI of the students was classified according to cut-off points for Asians and two groups were identified: underweight (n= 10) and normal weight (n= 25). Between the BMI groups, weight (p = 0.001, eta2 = 0.297), percent body fat (p < 0.001, eta2 = 0.442), waist girth (p = 0.004, eta2 = 0.225), hip circumference (p = 0.006, eta2 = 0.208), and maximum heart rate (p = 0.001, eta2 = 0.301) were significantly different. However, there was no difference in height (p = 0.390, eta2 = 0.022), waist-to-hip ratio (p = 0.225, eta2 = 0.044) and aerobic fitness (p = 0.348, eta2 = 0.027). Both underweight and normal weight groups had a higher percent body fat and lower V02 peak than the recommended levels. These results support and extend previous studies that Asians have a higher body fat percentage at the same BMI level as Caucasians.