Publication: Synthesis, Characterization Of 1,3-Diarylpropenes And Tricyclic Indolines And The Cytotoxic Activities Of 1,3-Diarylpropenes
Loading...
Date
2022-09
Authors
Tan Aik Sian
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Alkaloids are crucial nitrogen-containing compounds that exhibit diverse biological and pharmaceutical activity, regardless of the compound scaffold. Accordingly, it drives the synthesis of amido 1,3-diarylpropene and 6-5-4 tricyclic
indoline under the alkaloid class, potentially the chemotherapeutic agents for cancer treatment. In the first study, forty (40) 1,3-diarylpropene derivatives, designed analogs of stilbenoids and dihydrostilbenoids, were synthesized by the palladiumcatalyzed
reactions of 2-amidoiodobenzene derivatives with either estragole or eugenol.
Description
Keywords
Synthesis , Characterization Of 1 , 3-Diarylpropenes , Tricyclic Indolines , Cytotoxic Activities Of 1