Publication: Pancreas volume and fat deposition in type II diabetes mellitus
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Date
2022
Authors
Ramanaidu, Anusha A/P
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Abstract
Diabetes mellitus is a metabolic disease associated with a defect of β cell function
that causes insulin resistance characterised by hyperglycemia. In the diabetes mellitus
population, the reduction of pancreatic volume and an increase in the pancreas attenuation
cause uncontrolled sugar in patients. In patients with type II diabetes mellitus, there is a
strong association between pancreas volume and pancreatic attenuation. Many studies
conducted in Europe and other Asian countries showed diabetes mellitus has an
association with reduced pancreas volume and an increase in pancreas attenuation in
diabetes mellitus population. The aim of this study is to establish a significant reduction
in pancreatic volume and an increase in the pancreatic attenuation in type II diabetes
mellitus, in comparison with the non-diabetes mellitus population, based on the
assessment using computed tomography (CT) among the Malaysian population. In
Malaysia, no study has been conducted to evaluate pancreas changes among type II
diabetes mellitus patients. The various external factors such as lifestyle, diet, and body
habitus influence these pancreatic changes. Another objective is to see metabolic factors’
association with type II diabetes mellitus patients.
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Keywords
diabetes