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Immunogenicity Evaluation Of A133 And Ss-Ir: Development Of Vaccine Candidates Against Strongyloides Stercoralis

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dc.contributor.authorWong, Matthew Tze Jian
dc.date.accessioned2025-10-30T07:57:16Z
dc.date.available2025-10-30T07:57:16Z
dc.date.issued2024-02
dc.description.abstractStrongyloidiasis, caused by the nematode Strongyloides stercoralis, remains a threat to global public health. To date, a vaccine against strongyloidiasis remains unavailable and there was no significant development in this area after discovering the potential of recombinant protein Ss-IR as a vaccine candidate in 2011. In light of recent developments in the diagnosis of strongyloidiasis, A133 emerged in 2021 as an excellent diagnostic antigen, prompting curiosity for its potential as a vaccine candidate. Therefore, this study aimed to evaluate the efficacy of recombinant protein A133 in comparison to Ss-IR, as a potential vaccine candidate against S. stercoralis by investigating humoral and cellular immune responses in immunised mice.
dc.identifier.urihttps://erepo.usm.my/handle/123456789/23031
dc.language.isoen
dc.subjectStrongyloidiasis
dc.subjectVaccines
dc.titleImmunogenicity Evaluation Of A133 And Ss-Ir: Development Of Vaccine Candidates Against Strongyloides Stercoralis
dc.typeResource Types::text::thesis::doctoral thesis
dspace.entity.typePublication
oairecerif.author.affiliationUniversiti Sains Malaysia
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