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Preparation Of Dual-Dummy Template Magnetic Molecularly Imprinted Polymer For Magnetic Solid Phase Extraction Of Fluoroquinolone Antibiotics In Food

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dc.contributor.authorIsmail, Noorhafira
dc.date.accessioned2026-05-13T02:47:02Z
dc.date.available2026-05-13T02:47:02Z
dc.date.issued2025-03
dc.description.abstractFluoroquinolone antibiotics (fas) are widely used to treat humans and as veterinary medicine. A major concern was raised as the residue of fas may deposit in foods of animal’s origin, jeopardizing the food safety and causing antimicrobial-resistant to humans. Thus, an innovative and versatile adsorbent based on dual-dummy-template molecularly imprinted polymer-magnetic graphene oxide (ddmip-mgo) was fabricated for selective extraction and clean-up of fas from food samples. In this study, ddmip-mgo adsorbent was successfully synthesized with pipemidic acid and nalidixic acid as dual dummy templates molecular imprinted polymer (ddmip) with magnetic graphene oxide (mgo) nanoparticles coated on the surface of the newly synthesized dual dummy template. The ddmip-mgo provides feasibility of the adsorbent with specific recognition sites of ofloxacin (ofl), enrofloxacin (enro) and sparofloxacin (spar) in chicken meats and eggs samples to ensure efficient extraction prior to high performance liquid chromatography with ultraviolet detector (hplc-uv) analysis. The results showed that the ddmip-mgo exhibited uniform sizes, high magnetic responsivity, sensitivity and selectively recognition capability towards fas.
dc.identifier.urihttps://erepo.usm.my/handle/123456789/24203
dc.language.isoen
dc.subjectAntibiotics in food
dc.titlePreparation Of Dual-Dummy Template Magnetic Molecularly Imprinted Polymer For Magnetic Solid Phase Extraction Of Fluoroquinolone Antibiotics In Food
dc.typeResource Types::text::thesis::master thesis
dspace.entity.typePublication
oairecerif.author.affiliationUniversiti Sains Malaysia
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