Publication: Mechanism Of Neural Precursor Cell Expressed Developmentally Down-Regulated 4-Like (Nedd4l) As A Tumour Suppressor By Degrading Yes-Associated Protein (Yap) In Oesophageal Squamous Cell Carcinoma Through Hippo Pathway
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Date
2025-06
Authors
Wang, Weilong
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Abstract
The objective of this study was to investigate the role and related-mechanism of NEDD4L in OSCC. Firstly, the mRNA expression level of NEDD4L in OSCC was evaluated using the TCGA database and Firebrowse database, which confirmed that NEDD4L was highly expressed in para-cancerous tissues compared with cancer tissues.
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Keywords
Tumor suppressor proteins , Gene expression regulation