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Aptamer Technology: Adjunct Therapy for Malaria

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dc.contributor.authorKamarudin, Nik Abdul Aziz Nik
dc.date.accessioned2023-09-20T04:06:25Z
dc.date.available2023-09-20T04:06:25Z
dc.date.issued2018-10
dc.description.abstractMalaria is a life-threatening parasitic infection occurring in the endemic areas, primarily in children under the age of five, pregnant women, and patients with human immunodeficiency virus and acquired immunodeficiency syndrome (HIV)/(AIDS) as well as non-immune individuals. The cytoadherence of infected erythrocytes (IEs) to the host endothelial surface receptor is a known factor that contributes to the increased prevalence of severe malaria cases due to the accumulation of IEs, mainly in the brain and other vital organs. Therefore, further study is needed to discover a new potential anti-adhesive drug to treat severe malaria thus reducing its mortality rate. In this review, we discuss how the aptamer technology could be applied in the development of a new adjunct therapy for current malaria treatment.
dc.identifier.urihttps://erepo.usm.my/handle/123456789/17591
dc.language.isoen
dc.titleAptamer Technology: Adjunct Therapy for Malaria
dc.typeResource Types::other
dspace.entity.typePublication
oairecerif.author.affiliationUniversiti Sains Malaysia
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