Publication: Glycaemic changes from continuous glucose monitoring among children and adolescents with type 1 diabetes before and during fasting month in Ramadan
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Date
2022
Authors
Ramachandran, Puvanesvaran
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Abstract
Objective: We aimed to observe the changes and compare the glycemic parameters using CGMS before and during Ramadan using from 2 centers, and also to study glycemic variability during fasting and after breaking fast and to compare CGMS data from children with good and poor glycemic control. Method: This study was conducted in 2 tertiary centers: Hospital Putrajaya (HPJ) and Hospital Universiti Sains Malaysia (HUSM) from February to May 2020. Muslim T1DM patients between ages 8 to18, who expressed intention to fast were recruited and given Ramadan focused education. Self-monitoring of blood glucose (SMBG) and retrospective CGMS by iPro2® (Medtronic) was used to assess the glycaemic changes. Results: A total of 24 patients (12 female) were included with their mean age 13.6±3.1, HbAlc 9.6±1.9% and duration of illness 5.4±3.4 years. 91.7% were on multiple daily injections (MDI) and 8.3% on continuous subcutaneous insulin infusion (CSII). All had fasted without complications. CGMS analysis showed no changes in time in hyperglycaemia, time in hypoglycaemia, and time in range (TIR) for both periods before and during Ramadan fasting. Glycaemic variability as reflected by LBGI, HBGI, and MAGE, were also similar Conclusion: T1DM children and adolescents could fast safely in Ramadan, provided they are given focused education and compliant to SMBG. Ramadan fasting, in itself, is not associated with short-term glycaemic deterioration.
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Keywords
Type 1 Diabetes Mellitus , T1DM