Publication: Renal outcomes and predictors in spina bifida children:10 years review in two tertiary hospitals
| dc.contributor.author | Soddri, Nur Farhana | |
| dc.date.accessioned | 2026-06-16T04:20:46Z | |
| dc.date.available | 2026-06-16T04:20:46Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | specifically renal complications. The purpose of this study is to determine the long-term renal outcomes and their predictors in SB children. Materials and Methods: A 10-year retrospective record review was conducted involving pediatric patients who were diagnosed with SB. Baseline data including type of SB, level of spinal lesion, neurological sequalae (bladder, bowel incontinence, ability to walk), renal function and imaging findings (ultrasound, MCUG, DMSA) were documented. Descriptive analysis was performed for socio-demographic characteristics. Univariable analysis was conducted to screen independent variables. Multiple logistic regression analysis was used to determine the association between significant predictors for renal scarring and CKD. Results: A total of sixty SB children with mean age 11.8±3.8 years during data collection were recruited. Most of the lesions were at L5 and below. Majority were complicated with urinary (88.3%) and bowel incontinence (93.3%). Despite majority performed CIC, almost two-third had symptomatic UTI. One-third of them had both hydroureter and hydronephrosis and fifty percent were shown to have vesicoureteric reflux. The odds for developing renal scarring were 8.3 times in female compared to male (p=0.046). Half of the cohort progressed into CKD. The presence of hydroureter and hydronephrosis on ultrasound were identified as the significant factor for development of CKD (OR 3.8; 95%CI 1.239, 11.385). Conclusion: The presence of hydroureter and hydronephrosis were the predictors for development of CKD whereas female gender is associated with renal scarring. | |
| dc.identifier.uri | https://erepo.usm.my/handle/123456789/24392 | |
| dc.language.iso | en | |
| dc.subject | Spina bifida | |
| dc.subject | hydroureter | |
| dc.title | Renal outcomes and predictors in spina bifida children:10 years review in two tertiary hospitals | |
| dc.type | Resource Types::text::thesis::master thesis | |
| dspace.entity.type | Publication | |
| oairecerif.author.affiliation | Universiti Sains Malaysia |