Publication: Retrospective review of clinicohistopathologic characteristics of basal cell carcinoma and squamous cell carcinoma in patients operated on at department of plastic surgery, Hospital Kuala Lumpur from 2004-2018
| dc.contributor.author | San, Deborah Ding Ying | |
| dc.date.accessioned | 2026-03-17T08:04:33Z | |
| dc.date.available | 2026-03-17T08:04:33Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Introduction: Non-melanoma skin cancers (NMSC) are the most common skin cancer worldwide. Highest incidences have been reported among the Caucasian population. Asian countries display a lower prevalence of NMSC, however its onset in the region has been rising over time. Method: Histopathology reports of patients diagnosed with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) were retrieved from the clinic of the Plastic and Reconstructive Surgery Department in Hospital Kuala Lumpur from 2004 to 2018 and analysed. Results: A total of 777 patients, with a total of 1,346 lesions were reported from 2004 to 2018. BCC comprised 71.5% (555), and SCC 28.5% (222) of patient cases. A rise in incidence of BCC and SCC cases was observed from 2004 to 2018. Chinese patients made up for the majority of cases for both NMSCs, at 46.8% (260) and 59.4% (132) for BCC and SCC respectively, followed by Malay patients at 43.7% (242) and 29.2% (65), Indian patients at 4% (23) and 9% (20), and patients of other ethnicities at 5%(29) and 2%(5). Average age of onset for both NMSCs was above 60 years. Mean size (diameter) of lesions examined was 16.98 mm for BCCs (Standard deviation; SD=19) and 30 mm for SCCs (SD=30). For BCC, the nodular variant was the commonest histopathological subtype, making up 81% (742) of all lesions. The majority of SCCs were well differentiated, comprising 46% (198) of all lesions. A total of 866 (64.3%) of all lesions excised achieved adequate margin clearance, that of 63% (577) of BCCs and 67.2% (289) of SCCs. For SCCs, larger lesions >2cm were linked to poorer rates of histological margin clearance (Adjusted 95% CI (0.98-0.99), p = 0.002). Conclusion: Surgical excision remains as the most effective choice of treatment for NMSCs, compared with other existing techniques | |
| dc.identifier.uri | https://erepo.usm.my/handle/123456789/23798 | |
| dc.language.iso | en | |
| dc.title | Retrospective review of clinicohistopathologic characteristics of basal cell carcinoma and squamous cell carcinoma in patients operated on at department of plastic surgery, Hospital Kuala Lumpur from 2004-2018 | |
| dc.type | Resource Types::text::thesis::master thesis | |
| dspace.entity.type | Publication | |
| oairecerif.author.affiliation | Universiti Sains Malaysia |