Publication: A 3-year review of group-b streptococcus colonization in pregnancy and its perinatal outcome in Hospital Selayang
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Date
2022
Authors
Jayakumar, Yogan
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INTRODUCTION AND OBJECTIVE: There is an increase in the prevalence of GBS infection in pregnancy, which causes significant morbidity and mortality to both mother and baby. This retrospective study will evaluate the impact and outcome of pregnancy associated with GBS in Selayang Hospital from year 2017 till 2019. STUDY METHOD: This retrospective study was performed at Hospital Selayang over a three-year period between 1st January 2017 and 31st December 2019. Patients with GBS colonization were identified from their case note and laboratory investigation result. Those patients who had their high vaginal swab culture growing GBS bacteria were considered as patient with GBS colonization. Patient’s demographic, obstetric and neonatal data were documented in Performa (Appendix 1). Data analysis was carried out with SPSS version 26.0. RESULTS: A total of 31762 patients delivered at Hospital Selayang. From this a total of 344 patients were noted to have GBS colonization, making its prevalence of 1.09%. Out of 344 deliveries, 114 of babies were admitted to NICU for various reason. Majority (56.3%) of them were admitted in view of presumed sepsis as the infants showed early sign of infection. From our study noted, that Chinese mothers has a significant association and 1.92 likelihood of baby admitted to NICU compared to other ethnicity (Adj 95% CI (1.11, 3.30), p =0.02) when antibiotic variable was controlled. Meanwhile patients who were given antibiotics has 0.62 reduce likelihood of baby admitted to NICU compared to patients who did not receive intrapartum antibiotic prophylaxis (p = 0.004). CONCLUSION: The prevalence (1.09%) shown much lower than other literature review, as the sample size not as universal screening in general population of pregnant patients. Only those patients who came with excessive vaginal discharge, PROM, PPROM and preterm labour were screened. There is significant association between Chinese ethnicity and NICU admission. It shown that babies born to Chinese mothers with GBS infection more prone to get admitted to NICU compare to other race and foreigners.
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