Publication:
Extraction, Characterisation And Bioactivity Assessment Of Pectic-Polysaccharide From Cinnamomum Verum Using Deep Eutectic Solvent–Microwave Assisted Approach

dc.contributor.authorBeh, Chi Kin
dc.date.accessioned2026-06-09T07:28:52Z
dc.date.available2026-06-09T07:28:52Z
dc.date.issued2025-09
dc.description.abstractThe cosmetics market exhibited increasing demand in natural-based product with excellent anti-hyperpigmentation effects. Meanwhile, the research community is venturing on extraction solvents that is eco-sustainable. Despite increasing interest, a Deep Eutectic Solvent (DES) specifically tailored for polysaccharide extraction remained undeveloped. In response, a novel acidic DES was synthesized from cost-effective, readily available components: citric acid monohydrate and L-glutamic acid in a 1:1 molar ratio, using microwave-assisted heating (10 min, 360 W). The resulting DES exhibited an orange hue, attributed to the involvement of the Maillard reaction during synthesis, indicating a synergistic interaction between the parent compounds. Characterization revealed that the DES is hydrophilic and acidic, with full water miscibility. Physicochemical evaluations included pH, density, solubility, rheological behaviour, and FTIR spectroscopy, alongside Maillard reaction assessments. Molecular docking analysis further supported the presence of a robust hydrogen-bond network between the amine and carboxyl groups of glutamic acid, carboxyl groups of citric acid, and water molecules, stabilizing the supramolecular structure. This newly synthesized DES demonstrated strong potential for both laboratory-based research and scale-up for polysaccharide extraction
dc.identifier.urihttps://erepo.usm.my/handle/123456789/24358
dc.language.isoen
dc.subjectExtraction
dc.subjectCharacterisation And Bioactivity Assessment
dc.subjectPectic-Polysaccharide From Cinnamomum Verum
dc.subjectDeep Eutectic Solvent–Microwave Assisted Approach
dc.titleExtraction, Characterisation And Bioactivity Assessment Of Pectic-Polysaccharide From Cinnamomum Verum Using Deep Eutectic Solvent–Microwave Assisted Approach
dc.typeResource Types::text::thesis::doctoral thesis
dspace.entity.typePublication
oairecerif.author.affiliationUniversiti Sains Malaysia
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