Publication:
Expression Level of Pro-Apoptotic Genes Determine Disease Severity of HbE/Beta thalassemia

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Date
2019
Authors
Hassan, Rosline
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Research Projects
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Abstract
• Hb E/(3-thalassemia is inherited disorders that occur as a result of abnormal synthesis of (3-globin • Co-inheritance of a-globin hemoglobinopathies and increase level of HbF have shown to modulate the presentation of Hb E/~-thalassemia J but not in all patients~ suggesting that other factors may contribute to heterogeneity of the disease. • Hb E/~-thalassemia presented with a wide range of disease severity1 ranging from essentially asymptomatic to a severe transfusiondependent state
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Hodgkin
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