Publication: Expression Level of Pro-Apoptotic Genes Determine Disease Severity of HbE/Beta thalassemia
Loading...
Date
2019
Authors
Hassan, Rosline
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
• Hb E/(3-thalassemia is inherited disorders that occur as a result of
abnormal synthesis of (3-globin
• Co-inheritance of a-globin hemoglobinopathies and increase level of
HbF have shown to modulate the presentation of Hb E/~-thalassemia J
but not in all patients~ suggesting that other factors may contribute to
heterogeneity of the disease.
• Hb E/~-thalassemia presented with a wide range of disease severity1
ranging from essentially asymptomatic to a severe transfusiondependent state
Description
Keywords
Hodgkin