Publication: Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women
| dc.contributor.author | Ang, Xin Yee | |
| dc.date.accessioned | 2023-12-13T01:34:31Z | |
| dc.date.available | 2023-12-13T01:34:31Z | |
| dc.date.issued | 2022-09 | |
| dc.description.abstract | This study aimed to investigate the effects of lactobacilli probiotics in preventing the recurrences of vulvovaginal candidiasis (VVC) in 78 pregnant women with VVC (probiotic, n = 39; placebo, n = 39) and the potential benefits on quality of life. The lactobacilli probiotic (SynForU-HerCare; two capsules/day of 9.5 log CFU/capsule) or placebo was administered for 8-weeks in a randomized, double-blind, and placebo-controlled study. Subjects were assessed for vaginal and gut health conditions at week-0, 4, and 8 via questionnaires and analyzed vaginal microbiota and inflammatory changes. The vulvovaginal symptom questionnaire covered vulvovaginal symptoms and quality of life. Probiotic group was exhibited the reduction of irritation (P=0.023) and discharge (P=0.011) starting week-4 and continued after week-8 (P<0.05) as compared to the placebo. Probiotic group was exhibited the reduction of concern about symptoms after week-4 (P=0.010) and continued after week-8 (P=0.001), accompanied by reduced impairment of daily activities (P=0.012) and continued after week-8 (P=0.026). Probiotic group was exhibited the reduction of recurrences of both emotional and social stress compared to the placebo at both week-4 and week-8 (P<0.05). Probiotic group showed higher defecation times per week at week-4 (P=0.010) and week-8 (P=0.001) compared to the placebo group. | |
| dc.identifier.uri | https://erepo.usm.my/handle/123456789/17907 | |
| dc.subject | Effects Of Lactobacillus Spp. Against Vaginal | |
| dc.subject | Candidiasis In Pregnant Women | |
| dc.title | Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women | |
| dc.type | Resource Types::text::thesis::master thesis | |
| dspace.entity.type | Publication | |
| oairecerif.author.affiliation | Universiti Sains Malaysia |