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Comparison of tramadol and pethidine as treatment for perioperative shivering in caesarean section under spinal anaesthesia: A randomised-controlled trial

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Date
2021
Authors
Yaakop, Ahmad Firdaus
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Research Projects
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Abstract
Background: Perioperative shivering is a common and unpleasant complication. Current available modalities have variable efficacy and success. Currently pethidine is favoured but the search is on to look for agents with faster abolishment of shivering with fewer side effects. This study compared the efficacy of tramadol against pethidine in the treatment of perioperative shivering in patients undergoing caesarean section under spinal anaesthesia. Methods: A total of 42 patients scheduled for caesarean section under spinal anaesthesia who had experienced shivering were randomised into two groups, group T (n=21) received 1mg/kg tramadol and group P (n=21) received 0.5mg/kg pethidine. The outcomes measured include the time taken until shivering stopped, reduction in shivering severity, recurrence of shivering and incidence of side effects. Results: Median time taken from drug administration until cessation of shivering of the tramadol group was significantly faster than the pethidine group (7 minutes vs 13 minutes, P=0.049). Shivering grade 0 was achieved by minute 15 in the pethidine group compared to minute 10 in the tramadol group. However, there were no significant difference in terms of the number of recurrences of shivering (1 in tramadol vs 3 in pethidine group, P=0.606) and incidence of nausea (23.8% in tramadol vs 42.8% in pethidine group, P=0.19) between the two groups. Conclusion: Intravenous tramadol has faster alleviation of perioperative shivering than intravenous pethidine after spinal anaesthesia for caesarean section.
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tramadol , pethidine
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