Publication: Development, Optimization And Characterization Of Cisplatin Loaded Cubosomes For Human Lung Carcinoma
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Date
2025-06
Authors
Hassaan, Umar
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Abstract
Lung cancer remains a major global health challenge due to the limitations of conventional therapies. Platinum-based chemotherapy, such as cisplatin, is widely used but hindered by systemic toxicity and rapid clearance. To address these issues, we developed a novel glyceryl monooleate (GMO)-based cubosomes platform for sustained cisplatin delivery, leveraging its unique bicontinuous lipid structure to overcome encapsulation and release limitations of existing nanocarriers like liposomes and polymeric nanoparticles.
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Keywords
Cisplatin , Lungs—Cancer