Publication: Evaluation of ocular biometry in patients with evaporative dry eyes
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Date
2022
Authors
Wei, Ting Xiao
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Abstract
Introduction Accurate ocular biometry measurements is essential in ensuring good post-operative outcome. Laser interferometry is a commonly applied, noninvasive method of ocular biometry measurements which relies on stable tear film and smooth corneal surface for accurate readings. These are factors which are affected in patients with evaporated dry eye disease. Objective To evaluate ocular biometry parameters, which includes axial length, keratometry reading and anterior chamber depths among patients with evaporative dry eyes Methodology A cross-sectional study was conducted in ophthalmology clinic of Hospital Melaka and Hospital University Sains Malaysia from August 2019 till June 2021. The samples were selected with the convenience purposive sampling method. The participants who fulfilled the inclusion criteria were recruited. Participants were subjected to evaporative dry eye assessment, whereby they were divided into dry eye group and no dry eye group. The participants in both groups then undergo axial length, keratometry and anterior chamber depth measurements using IOLMaster 700. Result A total of 115 participants with mean age of 64.58 were recruited (64 had evaporative dry eye and 51 had no dry eye). Mean keratometry reading in the evaporative dry eye group was higher(-1.45D) than the no dry eye group (-0.59D) and the difference was statistically significant (p<0.01). Mean axial length and anterior chamber depth were shorter in the evaporative dry eye group. However, this was not statistically different. When assessing the correlation between individual dry eye parameters with ocular biometry of subjects with evaporative dry eye, there was a statistical significant positive correlation between anterior chamber depth with TBUT(p=0.021) and a statistically significant negative correlation between axial length with cornea fluorescein staining (p=0.042). There were no correlations between keratometry reading with OSDI, TBUT and cornea fluorescein staining grading. Conclusion There was a statistically significant difference in the mean keratometry reading between evaporative dry eye group and no dry eye group. However, there were no correlations between the individual dry eye parameter with keratometry reading among subjects with evaporative dry eye. Though differences in the mean axial length and anterior chamber depth were not statistically significant, correlations with the individual dry eye parameters were present. Therefore, assessment for evaporative dry eye during cataract operation pre-clerking is warranted to improve the accuracy of ocular biometry measurements and IOL power selection.
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