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Laparoscopic cholecystectomy; intraoperative cholangiography versus no intraoperative cholangiography. a multi center randomized control trial

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dc.contributor.authorZainudin, Nur Zawani
dc.date.accessioned2026-01-01T05:46:11Z
dc.date.available2026-01-01T05:46:11Z
dc.date.issued2019
dc.description.abstractIntroduction: Intraoperative cholangiography (IOC) is not something new in the world of laparoscopic cholecystectomy (LC). However it is still not a favorite method to be applied as a routine procedure in LC. Objectives: To determine the feasibility and safety of performing IOC during LC, to detect the incidence of undiagnosed pre-operative bile duct stone and to identify whether IOC can prevent bile duct injury. Method: Multi-center, double blinded randomize controlled trial done from 2016-2018. Total of 308 patients recruited and divided into 2 arms; with IOC and without IOC. Exclusion criteria includes in situ biliary stent placement, history of multiple laparotomies, performed. Out of 308 patients, 154 patients were assigned to IOC group and 154 patients were assigned to no IOC group. Results: There was a statistically significant difference of mean operation time between the group with IOC and no IOC (mean operation time for IOC group was 66.0 minutes (SD ±28.20) compared to no IOC group 55.6 minutes (SD±23.15), t statistics (df) = 306 (6.78), p-value <0.001). The successful rates for IOC was 98.1%. From 12 cases with presence of filling defects detected during IOC, 4 cases were confirmed CBD stones. Two were confirmed after conversion to CBDE and the other 2 cases were confirmed during ERCP performed. There was only 1 case of bile duct injury noted during IOC. No patients developed allergic reaction to contrast media and the post-operative complications were similar in both groups. Conclusion: IOC is a useful tool to delineate anatomy of bile duct during surgery. It also can easily been done by any surgeon with lots of practices and a proper guidance. Its use may be beneficial in selected cases.
dc.identifier.urihttps://erepo.usm.my/handle/123456789/23368
dc.language.isoen
dc.subjectintraoperative cholangiography
dc.subjectlaparoscopic cholecystectomy
dc.titleLaparoscopic cholecystectomy; intraoperative cholangiography versus no intraoperative cholangiography. a multi center randomized control trial
dc.typeResource Types::text::thesis::master thesis
dspace.entity.typePublication
oairecerif.author.affiliationUniversiti Sains Malaysia
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