Publication: The effectiveness of tachosil patch as a drainage and haemostatic agent in thyroid and salivary glands surgeries
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Date
2021
Authors
Lamry, Nur Adillah
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Abstract
Objectives: The aim of this study is to evaluate the effectiveness of TachoSil® patch as
a drainage and haemostatic agent in thyroid and salivary glands surgeries
Method: Twenty-seven patients who undergone thyroid and salivary glands surgeries
between June 2018 and May 2020 for benign pathology were included in the study. They
were classified into 2 groups; those who did not use TachoSil® patch intraoperatively
(known as non-Tachosil group) and those who used TachoSil® patch intraoperatively
(known as Tachosil group). Parameters such as duration of surgery, estimated blood loss,
post-operative drain amount, duration of drain and duration of hospital stay were used to
measure the outcomes in both groups.
Result: After 24 hours of surgery, mean drainage volume was reduced in Tachosil group
(20mL vs 45mL in non-Tachosil group, p=0.049). Drain removal occurred earlier in the
Tachosil group (2 days, as opposed to 2.5days in non-Tachosil group, p=0.045), which
resulted in a shorter duration of hospital stay (2 days, as opposed to 2.5d days for non-
Tachosil group).
Conclusion: This study demonstrated that TachoSil® is beneficial in reducing postoperative
drainage volume, which lead to reduction of drain duration, and eventually a
reduction in hospitalisation time. Considering that it was significant in providing
haemostasis intra-operatively, a bigger sample size future study is needed to adequately
assess its effectiveness.
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Keywords
Fibrin sealant patch , haemostatic agent