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Determination Of Epstein-barr Virus In Gastrointestinal Lymphomas (With Special Reference To Non-hodgkin's Lymphoma Of Small Intestine): Study On Malaysian Patients.

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dc.contributor.authorYunos, Asmah Md
dc.date.accessioned2026-02-04T02:59:36Z
dc.date.available2026-02-04T02:59:36Z
dc.date.issued2005-05
dc.description.abstractNon-Hodgkin's lymphoma (NHL) is ranked twelfth among all cancers world-wide, in which it is more prevalent in males compared to females. The aim of the present study was to determine the presence and distribution of Epstein-Barr virus (EBV) in non-Hodgkin's lymphomas (NHL) of the gastrointestinal tract (GIT) tissue samples obtained from 25 Malaysian patients diagnosed clinically and histopathologically. The gastrointestinal lymphomas analysed in the present study was divided into NHL of the ileocecal (9 cases), NHL of the small intestine (7 cases), NHL of the stomach (5 cases), NHL of the abdomen (1 case), NHL of the wedge ulcer (1 case), NHL of rectum fotic (1 case) and finally NHL of the hemicolon (1 case). The presence of EBV in all of the above mentioned tissue samples, after formalin fixation and paraffin embedding was carried out by using conventional in situ hybridization technology. Two out of 25 cases of NHL of the GIT analysed in the present study, demonstrated positive signals for EBV/EBER. In the first positive case, EBV/EBER signals were located in transformed lymphocytes in the serosa layer of the small intestine (14.3%). In the second EBV positive case, EBV/EBER signals were located in diffuse B-cell lymphomas of the ileocecal (11.1 %). In conclusion, these finding demonstrate a rare association between EBV and lower gastrointestinal lymphomas (excluding stomach).
dc.identifier.urihttps://erepo.usm.my/handle/123456789/23569
dc.language.isoen
dc.subjectMedicine
dc.subjectYunos
dc.subjectAsmah Md
dc.subjectDetermination Of Epstein-barr Virus In Gastrointestinal Lymphomas
dc.subjectNon-hodgkin's Lymphoma Of Small Intestine
dc.subjectStudy On Malaysian Patients
dc.subjectInstitut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute (AMDI)
dc.subject2005
dc.titleDetermination Of Epstein-barr Virus In Gastrointestinal Lymphomas (With Special Reference To Non-hodgkin's Lymphoma Of Small Intestine): Study On Malaysian Patients.
dc.typeResource Types::text::thesis::master thesis
dspace.entity.typePublication
oairecerif.author.affiliationUniversiti Sains Malaysia
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