Immediate outcome of mechanically ventilated terms babies in Hospital Kota Bharu and Hospital Universiti Sains Malaysia

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Date
2002
Authors
Che Mohd Razali, Che Hadibiah
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Publisher
Universiti Sains Malaysia
Abstract
Objectives:To determine the demographic profile, clinical characteristics and common causes of ventilation and complications among ventilated term babies weighing > 2.50 Kg and to determine the predictive factors for the outcome of these ventilated term babies. Methodology: A prospective study was conducted from 1st July 2000 until 31st December 2000 in Hospital Kota Bharu and from 1st January 2001 to 31st December 2001 in Hospital Universiti Sa ins Malaysia. All the term babies weighing more than or equal to 2.50 kilogram and received assisted ventilation were included in the study. Data regarding demographic and clinical characteristics were collected and all the complications that occurred during ventilation and the final outcome were documented. The predictors that determine the outcome were analysed using multiple logistic regression. Results: The proportion of male to female babies that required ventilation were 60.9°/o and 39.1 °/o respectively and more than 50°/o of babies weighed between 3.00 -3.49 Kg. The most common reasons for ventilation among term babies were asphyxia (42o/o), MAS (28%,), congenital pneumonia (21 °/o) and sepsis {9°/o). Many complications occurred while on ventilation like hypotension, seizures, PPHN and others. The significant predictors that determined the outcome of ventilated babies Were Apgar score less than 4 at 1 minute (p=0.001 ), intracranial haemorrhage (p=0.009), PPHN (p= 0.018) and pneumothorax (p=0.036). Conclusions: Asphyxia, MAS, congenital pneumonia and sepsis were the most common cause of ventilation and assisted ventilation was common among male babies. These results corresponded well to other studies. The complications that occured were mostly related to asphyxia and most causes of death were preventable.
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Keywords
Demographic profile, clinical characteristics of ventilated term babies
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