Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats

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dc.contributor.authorTiang, Ning
dc.date.accessioned2022-07-13T02:16:47Z
dc.date.available2022-07-13T02:16:47Z
dc.date.issued2021-02
dc.description.abstractIn this study, the protective effect of xanthone enriched fraction of G. mangostana (XEFGM) and α-MG were evaluated in an animal model of VaD induced by chronic cerebral hypoperfusion also known as- two vessel occlusion (2VO). In the first part of this study, XEFGM (25, 50, and 100 mg/kg) and α-MG (25 and 50 mg/kg) were administrated to 2VO rats and the rats were then subjected to behavioral test for learning and reference memory evaluation. The result suggested that, 50 mg/kg of α-MG treated 2VO significantly improved spatial learning and reference memory in Morris water maze test.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/15548
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectNeuroprotective Effectsen_US
dc.subjectXanthone-Enriched Fraction Garcinia Mangostanaen_US
dc.subjectAlpha-Mangostinen_US
dc.subjectChronic Cerebral Hypoperfusion Ratsen_US
dc.titleNeuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Ratsen_US
dc.typeThesisen_US
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