Effects Of Tualang Honey On Reproductive System Of Male Rats Exposed To Cigarette Smoke

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Date
2010-12
Authors
Mohamed, Mahaneem
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Publisher
Universiti Sains Malaysia
Abstract
Honey is traditionally consumed for enhancement of fertility by the Malays. Cigarette smoke (CS) has been postulated to produce oxidative stress resulting in abnormalities of male reproductive functions in human and animal studies. However, the protective effect of honey against these toxic effects has yet been reported. The objectives of this study, therefore, were (i) to characterise and assess the quality of Tualang honey, (ii) to determine the appropriate dose of honey that could enhance reproductive parameters, (iii) to determine the appropriate number of CS exposure that could reduce sperm count, and (iv) to determine the protective effects of honey against the toxic effects of CS on reproductive system of adult male Sprague-Dawley rats. Tualang honey at the dose of 0 (distilled water), 0.2, 1.2 or 2.4 g kg-1 daily for 4 weeks was given to the rats and the reproductive parameters were assessed. Rats were exposed to room air or CS for 8 minutes once, twice or thrice daily for 4 weeks and the sperm count was determined. In the subsequent study, the rats were given distilled water, honey, CS exposure or honey plus CS exposure. From 10 to 13 weeks of the study, each male rat was cohabited with 3 adult female rats for sexual behaviour and reproductive performance assessments.
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Keywords
Tualang Honey , Reproductive System
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