Effects Of Tualang Honey On Reproductive System Of Male Rats Exposed To Cigarette Smoke
Loading...
Date
2010-12
Authors
Mohamed, Mahaneem
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Honey is traditionally consumed for enhancement of fertility by the Malays.
Cigarette smoke (CS) has been postulated to produce oxidative stress resulting in
abnormalities of male reproductive functions in human and animal studies. However,
the protective effect of honey against these toxic effects has yet been reported. The
objectives of this study, therefore, were (i) to characterise and assess the quality of
Tualang honey, (ii) to determine the appropriate dose of honey that could enhance
reproductive parameters, (iii) to determine the appropriate number of CS exposure
that could reduce sperm count, and (iv) to determine the protective effects of honey
against the toxic effects of CS on reproductive system of adult male Sprague-Dawley
rats. Tualang honey at the dose of 0 (distilled water), 0.2, 1.2 or 2.4 g kg-1 daily for 4
weeks was given to the rats and the reproductive parameters were assessed. Rats
were exposed to room air or CS for 8 minutes once, twice or thrice daily for 4 weeks
and the sperm count was determined. In the subsequent study, the rats were given
distilled water, honey, CS exposure or honey plus CS exposure. From 10 to 13 weeks
of the study, each male rat was cohabited with 3 adult female rats for sexual
behaviour and reproductive performance assessments.
Description
Keywords
Tualang Honey , Reproductive System