Detecting schizophrenia in the prodromal phase: screening of genetic risk relatives

Simple item page
dc.contributor.authorSalleh, Mohd Razali
dc.contributor.authorOthman, Zahiruddin
dc.contributor.authorAlwi, Muhd Najib Mohd
dc.contributor.authorYassin, Mohd Azhar Mohd
dc.date.accessioned2021-03-25T07:17:40Z
dc.date.available2021-03-25T07:17:40Z
dc.date.issued2009
dc.description.abstractBackground: To screen and detect individuals at ultra high risk (UHR) for psychosis and evaluate the efficacy of a screening program. Methods: This a two-stage study involving relatives of patients with schizophrenia. The nonfirst degree relatives were additionally screened with the Screening Questionnaires ( SQ), besides the GHQ-12 and GAF in the first stage. All the positive subjects will proceed to the second stage assessment. Results: Sixty four (14.2 %) of 450 selective relatives were positive in the first stage. In the second stage, only 14 (3.1 %) were positive (UHR subject). The sensitivity of the SQ (67%) was much better than the GHQ (29%), but the specificity was not much difference. The d~t~ction rate of UHR individuals was higher in non-first degree relatives. Implications: Screening of genetic risk relatives is feasible. The high detection rate among non-first degree relatives is contributed by the addition of the SQ. The GHQ is not suitable for screening in early psychosis.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/12546
dc.language.isoenen_US
dc.publisherPusat Pengajian Sains Perubatan, Universiti Sains Malaysiaen_US
dc.subjectschizophreniaen_US
dc.titleDetecting schizophrenia in the prodromal phase: screening of genetic risk relativesen_US
dc.typeOtheren_US
Files
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Pusat Pengajian Sains Perubatan - Monograf