An Assessment Of Osteoporosis Condition And Knowledge Among Warfarin Users At A Hospital In The Northern Region Of Peninsular Malaysia

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Date
2017-01
Authors
Abdulameer, Aseel Hadi
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Publisher
Universiti Sains Malaysia
Abstract
Osteoporosis is a chronic disease that has a complex relation with patients using warfarin. In order to provide optimal management of osteoporosis, there is a need to advice patients about the usage of warfarin. A clinical part involved casecontrol study of a convenient sample of 270 subjects (controls and patients) recruited to assess the bone health status by measuring the bone mineral density (BMD) using quantitative ultrasound scan (QUS) as well as to evaluate their osteoporosis knowledge (OKT). The result of QUS showed that the prevalence of normal BMD, osteopenia, and osteoporosis were 23.3%, 53.7%, 23% respectively. This study showed that more than three-quarter patients group (82%) were at high risk of abnormal body mass density (BMD). The warfarin users were two times more likely to have a higher osteoporosis risk compared to control group. Moreover, BMD has a negative correlation with age, but has a positive correlation with body mass index (BMI). Patients showed a negative correlation with a higher dose of warfarin intake. In addition, odd ratio of females using warfarin scored higher incidence of osteoporosis by 2.4 times more than females who did not use warfarin. In this regard, Chinese females (more than 50 years old), under warfarin therapy for more than one year, were more affected for the reduction in BMD as compared to Malay or Indian females. In conclusion, patients who used warfarin are at a higher risk of osteoporosis than the controls.
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Keywords
An Assessment of osteoporosis condition , knowledge among warfarin users
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