An Assessment Of Osteoporosis Condition And Knowledge Among Warfarin Users At A Hospital In The Northern Region Of Peninsular Malaysia
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Date
2017-01
Authors
Abdulameer, Aseel Hadi
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Osteoporosis is a chronic disease that has a complex relation with patients
using warfarin. In order to provide optimal management of osteoporosis, there is a
need to advice patients about the usage of warfarin. A clinical part involved casecontrol
study of a convenient sample of 270 subjects (controls and patients)
recruited to assess the bone health status by measuring the bone mineral density
(BMD) using quantitative ultrasound scan (QUS) as well as to evaluate their
osteoporosis knowledge (OKT). The result of QUS showed that the prevalence of
normal BMD, osteopenia, and osteoporosis were 23.3%, 53.7%, 23% respectively.
This study showed that more than three-quarter patients group (82%) were at high
risk of abnormal body mass density (BMD). The warfarin users were two times more
likely to have a higher osteoporosis risk compared to control group. Moreover, BMD
has a negative correlation with age, but has a positive correlation with body mass
index (BMI). Patients showed a negative correlation with a higher dose of warfarin
intake. In addition, odd ratio of females using warfarin scored higher incidence of
osteoporosis by 2.4 times more than females who did not use warfarin. In this
regard, Chinese females (more than 50 years old), under warfarin therapy for more
than one year, were more affected for the reduction in BMD as compared to Malay
or Indian females. In conclusion, patients who used warfarin are at a higher risk of
osteoporosis than the controls.
Description
Keywords
An Assessment of osteoporosis condition , knowledge among warfarin users