Pharmacoeconomic Analysis Of Uncomplicated Hypertension In Ambulatory Care Clinic
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Date
2011-02
Authors
Ahmad Al-Efan, Qais Mohammad
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Abnormal elevation in BP is associated with cardiovascular and renal diseases.
Prevalence of hypertension in subjects aged ≥ 15 years is 27.8% in Malaysia. Studies
have reported high direct and indirect costs are attributable to hypertension.
Pharmacoeconomics implements and applies methodologies of health economics to the
field of pharmaceuticals and pharmaceutical policy. Malaysia lacks data on how much it
cost to treat hypertension and what is the size of the economic burden of hypertension.
This study was done to: 1) estimate the cost of treating uncomplicated hypertension, 2)
estimate the impact of uncontrolled BP on ambulatory care resources, and 3) evaluate
the cost-effectiveness of different antihypertensive drug classes.
Prospective data collection of a cohort of hypertensive patients who had signed the
informed consent sheet and followed up for one year were analyzed retrospectively to
determine the costs (direct and indirect) attributable to uncomplicated hypertension.
Cost-effectiveness ratios of different antihypertensive drug classes were calculated and
compared. Nonparametric tests (i.e., Kruskal Wallis and Mann-Whitney) were used to
determine the statistically significant differences in costs and a p value of < 0.05 was
defined as statistically significant.
Description
Keywords
Uncomplicated Hypertension , Ambulatory Care Clinic