Normal pituitary gland on magnetic resonance imaging: size, shape and appearance in Kelantan population

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Date
2002
Authors
Abdul Muthalib, Fairos
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Publisher
Universiti Sains Malaysia
Abstract
Magnetic Resonance Imaging provides sufficient high resolution to analyzed the size, shape and appearance of the pituitary gland. So far, no research has been performed with regards to the morphology and measurement of pituitary gland in Kelantan population. The aim was to determine the measurement and morphology of normal pituitary gland in the population of this state. This prospective study was done from June 1999 till December 2000 in HUSM, Kubang Kerion. Inclusion criteria for this study include no clinical finding suggestive of pituitary disease or significant endocrine disturbance for the initial radiological referral. Midline noncontrast- enhanced Tl-Weighted Images (TlWI) via sagittal images was used exclusively for the analysis. Total of eighty patients were included in this study with age of patients range from 0.08 to 87 years. The mean height of the gland in male patient was 5.56 mm ± (SD 1.596) and for female 5.97 mm ± SD 1.76. In the age group of 10 to 19 years old, an increase in size and convexity of the pituitary gland presence during adolescence. The mean height, length and width of the infant pituitary gland were 3.56 mm, 6.20 mm and 5.61 mm respectively. The signal intensity in the anterior lobe of the pituitary gland in infant was of high signal intensity relative to the pons. The posterior lobe demonstrated high signal intensity in 62 patients (77.50fo). The mean diameter of the infundibulum on coronal view was 1.854 mm with range of 0.5 to 3.9mm. This study confirms that there were correlation between the age pituitary size and shape. It also provides data and information regarding normal variants of the pituitary gland.
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Keywords
pituitary gland
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