ERECTILE DYSFUNCTION PATIENTS IN INSTITUT UROLOGI & NEFROLOGI (IUN), HOSPITAL KUALA LUMPUR (HKL) AND CLINICAL TRIAL WITH TRANSURETHERAL ALPROSTADIL (MUSE®)
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Date
2001
Authors
NOOR AZAM, NASUHA
Journal Title
Journal ISSN
Volume Title
Publisher
Pusat Pengajian Sains Perubatan Universiti Sains Malaysia
Abstract
The aim of this study was to evaluate the factors contributing towards erectile
dysfunction (ED) in patients followed-up in the Institut Urologi & Nefrologi, Hospital
Kuala Lumpur between 1st
. March 1999 to 31st
. August 1999. One hundred and fiftyfour
patients were included in this study. The mean age of the patients was 52.68 years.
The youngest was 22 and the oldest was 76 year-old. Most were between the age of 45
and 65 year-old.
Diabetes mellitus and hypertension played a major role as contributing factors in the
overall study population. 45.4% of the patients have diabetes mellitus and 29.2% have
hypertension. 41.5% of the patients have single contributing factor towards erectile
dysfunction whereas 29.2% have two and 10.4% of the patients have three contributing
factors. In 18.2% of the studied patients the cause of ED were unknown. In term of
racial distribution, Malays contributed 48.7% of the study sample; Indian 25.3% and
Chinese constitute about 22.1 %.
35 patients who fulfilled the inclusion criteria were enrolled in the clinical trial with
transurethral alprostadil (MUSE®). Thirty patients (85.6%) completed the in-clinic
titration phase. Of these, 18 patients (60%) responded well to the MUSE® and they
were sent home with the medication. However only 33.3% of patients completed the
home phase.
In conclusion, diabetes mellitus plays an important role in our patients with erectile
dysfunction and MUSE® is one of the alternative treatment for such condition.
Description
Keywords
General Surgery