Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound

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dc.contributor.authorAbidin, Mohd Radhwan
dc.date.accessioned2020-03-17T08:47:55Z
dc.date.available2020-03-17T08:47:55Z
dc.date.issued2018
dc.description.abstractBackground: MR-HIFU is a technological breakthrough for non-surgical approach for treating tumour. MR-HIFU is safe with many advantages however complications may occur, at target and the near-field region. Specific ultrasound setup at MR-HIFU console must be made prior to ablation process, which can affect the near-field temperature. The purpose of this study was to investigate how intersonication cooling time and sonication power influence the near-field temperature. Methodology: Philips QA phantom was used for ablation. A total of 100 ablations were made with different intersonication cooling time, which are 30 s, 60 s, 90 s and 120 s and different sonication power, which are 40 W, 80 W, 120 W, 160 W and 200 W. The near-field region was taken at 2cm from the base of phantom. The data were evaluated using statistical analysis. Level of significance was determined (p < 0.05). Results: There was no significant correlation between intersonication cooling time and the near-field temperature, with p = 0.089. However, there is a significant correlation between sonication power and the near-field temperature with p = 0.001. Regression analysis indicates that the sonication power significantly predicted the temperature changes [R2 = .416, F(1,18) = 14.533, p = .001] Conclusion: There is no relationship between intersonication cooling time with near-field temperature. However, there is relationship between sonication power and near-field temperature.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/9657
dc.language.isoenen_US
dc.publisherPusat Pengajian Sains Perubatan, Universiti Sains Malaysiaen_US
dc.subjectMagnetic resonance imagingen_US
dc.titleStudy on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasounden_US
dc.typeThesisen_US
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