Synthesis, characterization and in vitro evaluation of cytotoxic potential of mono, di, tri and tetra N-heterocyclic carbene silver(I) complexes.

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Date
2017-05
Authors
Fatima, Tabinda
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Universiti Sains Malaysia
Abstract
Tesis ini memaparkan tentang sintesis, pencirian dan penilaian potensi sitotoksik in vitro untuk dua puluh enam kompleks baru mono, di, tri dan tetra NHC-Ag(I) yang dihasilkan daripada dua puluh enam garam baru mono, bis, tris dan tetrakis benzimidazolium. Empat siri garam yang mempunyai terminal N-pergantian yang simetrikal telah disediakan. This thesis presents the synthesis, characterization and in vitro evaluation of cytotoxic potential of twenty six new mono-, di-, tri- and tetra-NHC-Ag(I) complexes derived from twenty six new mono-, bis-, tris- and tetrakis- benzimidazolium salts. The four series of salts with symmetrical terminal N-substitution were prepared.
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Keywords
Evaluation , Cytotoxic
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