Single Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Lines

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dc.contributor.authorYang, Kok Lee
dc.date.accessioned2022-07-13T01:59:07Z
dc.date.available2022-07-13T01:59:07Z
dc.date.issued2021-01
dc.description.abstractHevea brasiliensis rubber latex dialysed C-serum supernatant (DCS) sub-fraction has been reported to possess potential anti-proliferation activities against specific human breast (MDA-MB-231) and liver (HepG2) cancer cell lines through autoschizis cell death pathway. Further investigations on DCS treatment (concentrations ranged between 0 to 100 μg/mL) on anti-proliferative effect in this study have shown that IC50 of DCS was at 8.81 μg/mL and 22.12 μg/mL for DBTRG (human brain glioblastoma) and MKN74 (human gastric tubular adenocarcinoma), respectively. Although DCS showed specificity in cancer cell lines based on cell viability assays, its genotoxicity effects are important in view of its employment in human subjects if it would be developed into an anti-cancer drugen_US
dc.identifier.urihttp://hdl.handle.net/123456789/15547
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectSingle Agent And Synergistic Activityen_US
dc.subjectLatex C-Serumen_US
dc.subjectLed Red Lighten_US
dc.subjectCancer Cell Linesen_US
dc.titleSingle Agent And Synergistic Activity Of Latex C-Serum With Led Red Light In Cancer Cell Linesen_US
dc.typeThesisen_US
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