Pusat Pengajian Sains Kajihayat - Tesis

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    Efficacy And Autodissemination Of Aedestech Mosquito Home System (Amhs) On Aedes Mosquitoes In Laboratory And Small-scale Field Study
    (2024-09)
    Universiti Sains Malaysia
    Ovitrap deployment stands as a viable strategy for Aedes mosquito control. This study evaluated the efficacy of an autodissemination ovitrap called AedesTech Mosquito Home System (AMHS), which incorporates pyriproxyfen. This study encompassed laboratory trials and a small-scale field study. The objective of the field study was to comprehensively assess the impact of AMHS on Aedes, non-target insects, and dengue infection rates in mosquitoes. Within the laboratory trials, these investigations unfolded across two species of mosquitoes: Aedes albopictus and Aedes aegypti. Three distinct facets were explored in the laboratory trials: the influence of an attractant on the oviposition, the effect of trap positioning on oviposition, and the selection of oviposition sites. The field study conducted in Asoka Apartment, Pulau Pinang, unfolded in three successive periods: baseline study, effectiveness study, and autodissemination study. Concurrently, the accuracy of the AedesTech Mobile App (ATA) was scrutinized. The laboratory results indicated the Mosquito Home Aqua (MHAQ) solution with attractant consistently attracted Ae. aegypti effectively (Welch's ANOVA, F(2,68.66)=5.22,p=0.01). However, its efficacy with Ae. albopictus was suboptimal compared to other treatments (Two-way ANOVA, F=0.16,df=2,p>0.05), highlighting the need for considering additional attractants. Notably, the placement of AMHS exhibited no discernible impact on its attractiveness for both mosquito species (T-test,p>0.05), underscoring the flexibility in trap deployment.
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    Biochemical Characterization And Analysis Of Moringa Oleifera Seeds On Mcf7 Cells
    (2019-07)
    Ismail Abiola, Adebayo
    In this study, the antioxidant activity of the plant seed and its antiproliferative effect against Michigan Cancer Foundation-7 (MCF7) breast cancer cells were investigated, and the underlying mechanisms of actions involved were unravelled using molecular biological methods such as 2-dimensional gel electrophoresis (2- DE), western blotting and reverse transcription polymerase chain reaction (RT-PCR). l,l-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis-3-ethylbenzthiazoline-6- sulphonic acid (ABTS) tests showed that all the extracts and fractions from the seeds have antioxidant capacities.
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    Prevalence Of Gastrointestinal Parasites Of Semi-Captive Orangutans (Pongo Pygmaeus) In Bukit Merah Orang Utan Island, Perak, Malaysia
    (2019-08)
    Saad, Nurulanis Safia
    This study was conducted to examine the prevalence of gastrointestinal parasites in twenty-one semi-captive orangutans (Pongo pygmaeus) in Bukit Merah Orang Utan Island, Perak. Samples were collected twice monthly with three replicates in period of one year (December 2014-December 2015). Five methods were used to screen for gastrointestinal parasites, protozoan parasites and parasitic eggs of worm.
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    Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds
    (2019-07)
    Mat Junoh
    The aim of this study is to fabricate a new material by combining hydrophobic and hydrophilic materials. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) has adequate flexibility for medical applications, however, its lack of hydrophilic properties limits its applications in this field. Therefore, the P(3HB-co-4HB) polymer was blended with gelatin using two different techniques; freeze-drying and electrospinning. The former technique can produce porous scaffolds by manipulating various parameters including 4HB monomer content, gelatin concentrations, and total weight of the scaffolds. The surface morphology results of the blend scaffolds at 27 mol%4HB and 50 mol%4HB have high porosity but the porosity of the blend scaffold decreased at 82 mol%4HB.
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    Antibacterial And Antibiofilm Activities Of Ethyl Acetate Extract Of Nigrospora Sphaerica Cl-Op30 Isolated From Swietenia Macrophylla Leaf
    (2019-07)
    Ahmad Mokhtar, Nur A’fina
    This research was aimed to study antibacterial and antibiofilm activities of an endophytic fungus Nigrospora sphaerica CL-OP30 isolated from Swietenia macrophylla plant. Quantitative measurement of antibacterial activity revealed that this endophyte produced the highest antibacterial activity at day 12 of cultivation.