ADHERENCE TO MEDICATION AMONG HYPERTENSIVE OUTPATIENTS IN THE PENANG GENERAL HOSPITAL, MALAYSIA

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dc.contributor.authorTurki Suleiman, Amal Khalil
dc.date.accessioned2016-01-12T03:30:32Z
dc.date.available2016-01-12T03:30:32Z
dc.date.issued2010-06
dc.description.abstractAdherence to antihypertensive medications in general is not well documented in developing countries, and what is known is far from encouraging. Despite the effectiveness of antihypertensive treatment, medication adherence is often suboptimal in hypertensive Malaysian population. This retro-prospective coh011 study aimed to assess the medication adherence, and factors affecting this. A cohort of 380 hypertensive patients was conveniently recmited from the outpatient hypertension clinic at Penang General Hospita], lv1alaysia. The Morisky self-rep011 scale revealed that 51.3% patients (n= 195) had poor adherence to prescribed antihypertensive medication. A Semistmctured interview revealed forgetfulness due to a lack of symptoms; poor social supp011, medication side effects, and the perception that long-term medication may be addictive were principal factors of poor adherence to medication. The structural equation modelling (SEM), which identified the multivariate hypothesized predictors of poor adherence to medication, showed that a lack of self discipline, aversion towards medication, and a negative attitude towards medication in general negatively accounted for 75% of factors affecting medication adherence. The one-way ANOVA and independent t-tests of independent samples revealed no statistically significant differences (p>0.05 for all) between adherent and non-adherent patients with regards to demographic variables, including age, gender, family history of hypertension, race, educational level, and income. A significant association was found between patients had signit1cantly better adherence if they had an increased daily frequency of doses than XVII once daily regimens (p<O.OO 1 ). The linear regressiOn analysis showed that poor medication adherence was a statistically significant (p<O.O 1) independent predictor of uncontrolled blood pressure. Uncontrolled blood pressure was also a significant independent predictor of abnormalities in the lipid profile and glucose levels (p<0.05). Finally, a significant association \vas found in this cohort between poor adherence to medication and an increased risk of hospital admission (p<O.OOI). Based on these results, health care providers should aim to enhance the awareness of patients about the importance of antihypertensive medications and assess the level of social support to optimize their adherence to medication. The healthcare provider may tailor more sensitive interventions programs to suit the unique needs of each patient. They are more at risk of coronary and cerebrovascular diseases and are more likely to experience hospital admission. Therefore, medication adherence is one of the crucial mediators between the aims of medical practice and the ultimate outcome for patients.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/1388
dc.subjectADHERENCE TO MEDICATION AMONG HYPERTENSIVEen_US
dc.titleADHERENCE TO MEDICATION AMONG HYPERTENSIVE OUTPATIENTS IN THE PENANG GENERAL HOSPITAL, MALAYSIAen_US
dc.typeThesisen_US
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