In Vitro Study Of The Efficacy Of Six Ethnoveterinary Plants Species Against Parasitic Nematodes And Caenorhabditis elegans In Nigeria

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dc.contributor.authorGagman, Haladu Ali
dc.date.accessioned2019-04-04T01:45:39Z
dc.date.available2019-04-04T01:45:39Z
dc.date.issued2018-06
dc.description.abstractControl of trichostrongylid nematodes using synthetic drugs have resulted to several complications such as increasing resistance of the nematodes to synthetic drugs, change in the quality of the products from the treated animals due to drugs residues in the tissues of the animals. These called for research to explore alternative to conventional drugs. The purpose of this work was to carry out in vitro study of the aqueous and methanol extracts Detarium microcarpum, Guiera senegalensis, Cassia siamea, Parkia biglobosa, Gmelina arborea and Boswellia dalzielii against trichostrongylid nematodes of small ruminants and the ivermectin resistant strain of Caenorhabditis elegans DA1316. The powdered stem bark of each plant was extracted by maceration in water and methanol. Phytochemical screening of the extracts revealed the presence of alkaloids, flavonoids, tannins, phenolic compounds, steroids and terpenoids but were not equally distributed among the types of plants and between aqueous and methanol extracts. The plant extracts were tested in vitro against the motility of L3 larvae of trichostrongylid nematodes at the concentrations of (0.2, 0.4, 0.6, 0.8 1.0 and 2.0 mg/ml). Detarium microcarpum was the most potent plant according to the standard of World Association for the Advancement of Veterinary Parasitology (WAAVP), as the aqueous and methanol extracts inhibited up to 90% motility of the larvae. Guiera senegalensis was the second most potent plant for inhibiting 80% and 90% by aqueous and methanol extracts respectively. The extracts of C. siamea which were moderately effective at 2.0 mg/ml was the third most effective plant.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/7931
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectEfficacy of six ethnoveterinary plants speciesen_US
dc.subjectagainst parasitic nematodes in Nigeriaen_US
dc.titleIn Vitro Study Of The Efficacy Of Six Ethnoveterinary Plants Species Against Parasitic Nematodes And Caenorhabditis elegans In Nigeriaen_US
dc.typeThesisen_US
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