Effect Of Blood Donation On Blood Donor Cardiorespiratory Fitness Level
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Date
2017
Authors
Mail, Jamaludin
Journal Title
Journal ISSN
Volume Title
Publisher
Universiti Sains Malaysia
Abstract
Background. Blood donation is vital to meet patients’ needs for blood and blood products.
However, reduction of haemoglobin, haematocrit and blood volume following blood donation
might affect the cardiorespiratory fitness level. The aim of this study is to determine the effect
of blood donation on the level of cardiorespiratory fitness as measured by predicted maximum
oxygen uptake (VO2 max).
Methods. A total of 42 male blood donors were involved in this cross sectional study with 14
participants each for poor, average and excellent fitness groups. The 20 meters Multistage
Shuttle Run fitness test protocol was used to measure cardiorespiratory fitness level. The test
was performed 24 hours before and after a 450 ml whole blood donation. Simultaneously,
haemoglobin and haematocrit were assessed 24 hours before, immediately after and 24 hours
after the donation.
Results. The median baseline pre-donation predicted VO2 max were 33.30 (30.73, 35.50),
38.85 (36.80, 42.65) and 50.80 (50.20, 52.60) ml/kg/min for poor, average and excellent fitness
groups, respectively. The cardiorespiratory fitness level were slightly reduced at 24 hours after
blood donation by 0.61%, 1.29% and 3.43% in the for poor, average and excellent fitness
groups, respectively. However, the reduction was only statistically significant in the excellent
fitness group (p = 0.017). The haemoglobin and haematocrit significantly reduced for all
groups at 24 hours after donation. The haemoglobin was reduced by 7.63% (p < 0.001), 7.82%
(p < 0.001) and 5.46% (p < 0.001) for poor, average and excellent fitness groups, respectively.
The haematocrit was reduced by 8.40% (p < 0.001), 9.08% (p < 0.001) and 7.21% (p = 0.002)
for for poor, average and excellent fitness groups, respectively. The Spearman correlation
analysis revealed no significant relationship between haemoglobin changes and predicted VO2
max changes in all groups, poor fitness level group (rs = 0.001), average fitness level (rs =
0.639) and excellent fitness level group (rs = 0.532).
Conclusion. The cardiorespiratory fitness level was slightly reduced at 24 hours following a
450 ml whole blood donation, which was concomitant with significant haemoglobin and
haematocrit reduction. However, there was no significant relationship between the changes in
haemoglobin and cardiorespiratory fitness after blood donation.
Description
Keywords
Blood donation, Cardiorespiratory fitness , VO2 max, Haemoglobin, Haematocrit