A novel inhibitor of sirtuin: Elucidation of mode of action and molecular pathway in colorectal cancer cell line.

dc.contributor.authorYi Jer, Tan
dc.date.accessioned2018-07-23T04:07:28Z
dc.date.available2018-07-23T04:07:28Z
dc.date.issued2017-08
dc.description.abstractKanser kolon merupakan salah satu jenis kanser yang paling banyak didapati di seluruh dunia. Walaupun kebanyakan pesakit menunjukkan respon yang baik terhadap rawatan kimoterapi pada peringkat awal, akan tetapi terdapat banyak kes kanser berulang selepas rawatan yang disebabkan oleh kewujudan rintangan terhadap rawatan, maka wujudnya keperluan untuk membangunkan agen terapeutik baru untuk kanser kolorektal. Colorectal cancer (CRC) is one of the most common types of cancer worldwide. Although most patients are responsive to standard chemotherapy treatments at the initial stage of diagnosis, many succumb to relapse due to acquired chemoresistance, hence driving the need for the development of novel therapeutic agents for colorectal cancer.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/6000
dc.language.isoenen_US
dc.publisherUniversiti Sains Malaysiaen_US
dc.subjectMolecularen_US
dc.subjectCanceren_US
dc.titleA novel inhibitor of sirtuin: Elucidation of mode of action and molecular pathway in colorectal cancer cell line.en_US
dc.typeThesisen_US
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