A Study On Central Corneal Thickness And Intraocular Pressure In Preterm Malay Newborns
| dc.contributor.author | Prem Kumar, Vindhya | |
| dc.date.accessioned | 2017-09-07T07:40:03Z | |
| dc.date.available | 2017-09-07T07:40:03Z | |
| dc.date.issued | 2015-11 | |
| dc.description.abstract | INTRODUCTION Central corneal thickness (CCT) and intraocular pressure (IOP) are important predictors of glaucoma development. As survival rate of preterm newborns increase due to medical advancement, many preterm related ophthalmological conditions that give rise to increased CCT and accuracy of IOP measurements emerge. However, very few studies have reported about CCT and IOP in preterm newborns. No studies have been done in South East Asia on CCT and IOP in preterm newborns. Since normal values for CCT differs in different races, only Malay preterm newborns were recruited for this study, to establish normative data in Malaysia. OBJECTIVES To compare the mean CCT and mean IOP among very preterm, moderate preterm and control group of full term newborns and to determine their correlation. METHODS A comparative cross sectional study was done in Hospital Universiti Sains Malaysia (Hospital USM) between the period of October 2013 till April 2015. CCT and IOP of 99 preterm and full term newborns were measured by convenient sampling based on the predetermined exclusion and inclusion criteria using the iPac, Reichert portable pachymeter and Icare, portable tonometer. Newborns were divided into very preterm moderate preterm and control group of full terms. Mean CCT and mean IOP was measured and compared among the 3 groups. All values were entered into a data collection sheet and these values were analyzed using SPSS software. xv RESULTS A total of 99 newborns were examined. Thirty one were very preterm newborns with mean gestational age of 29.8 ± 1.1 weeks (ranging 28-31weeks), 32 were moderate preterm with mean gestational age of 33.1 ± 0.9 weeks (ranging 32-35 weeks) and 36 were full term with mean gestational age of 37.4 ± 0.5 weeks (ranging 37-38 weeks). The mean CCT was 581.6 ± 57.7 μm, 557.6 ± 36.6 μm and 559.8 ± 19.5 μm for very preterm, moderate preterm and full term newborns respectively. The mean IOP in the very preterm group was 15.1 ± 4.1 mmHg, in the moderate preterm group was 11.3 ± 3.5 mmHg and in the full term group was 15.5 ± 2.2 mmHg. There was a statistically significant difference between the mean CCT (p = 0.040) and IOP (p <0.001) in the very preterm, moderate preterm and full term category. There was a statistically significant and fair correlation found between CCT and IOP in the preterm category (r = 0.337, p = 0.007). However no statistically significant correlation was documented between CCT and IOP in the full term category ( r = 0.198, p = 0.247). CONCLUSION Very preterm newborns had significantly thicker CCT and increased IOP when compared to the moderate preterm and full term newborns. CCT was fairly correlated to IOP in preterm newborns. | en_US |
| dc.identifier.uri | http://hdl.handle.net/123456789/4526 | |
| dc.language.iso | en | en_US |
| dc.publisher | Universiti Sains Malaysia | en_US |
| dc.subject | Central corneal thickness | en_US |
| dc.subject | in preterm Malay newborns. | en_US |
| dc.title | A Study On Central Corneal Thickness And Intraocular Pressure In Preterm Malay Newborns | en_US |
| dc.type | Thesis | en_US |
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